Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P0CK60
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P0CK60
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0CK60 | |||||
No associated diseases with P0CK60
1 regional properties for P0CK60
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Alpha carbonic anhydrase domain | 28 - 64 | IPR001148 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| host cell nucleus | A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
8 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| endodeoxyribonuclease activity, producing 5'-phosphomonoesters | Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters. |
| metal ion binding | Binding to a metal ion. |
| nucleotidyltransferase activity | Catalysis of the transfer of a nucleotidyl group to a reactant. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA helicase activity | Unwinding of an RNA helix, driven by ATP hydrolysis. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA replication | The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. |
| protein-DNA covalent cross-linking | The formation of a covalent cross-link between DNA and a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAVNWVFTL | NFAGEVPVLS | FDERVQYAVW | QHERVNHDHI | QGVIQLKKKA | KMNTVKNIIG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GNPHLEKMKG | SIEEASAYAQ | KEESRVAGPW | SYGELLKKGS | HKRKIMELIK | DPENELEEPQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KYRRAMAWSA | MDESRKLAEE | GGFPYTLYSW | QETVLGLLEE | EPNDRIIIWV | YGPNGNEGKS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QFGKFLGLKK | DYLYLPGGKT | QDMTYMLMKN | PKANVVMDIP | RCNSEYLNYQ | FMELIKNRTI |
| 250 | 260 | 270 | 280 | ||
| FSYKYEPVGC | IINNKIHVIV | LANVLPDYEK | ISQDRIKIIY | C |