P0CK06

PR
Gene name
Protein name
P3N-PIPO polyprotein
Names
Species
Potato virus Y (strain Hungarian) (PVY)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-196 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P0CK06

Entry ID Method Resolution Chain Position Source

No variants for P0CK06

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0CK06

No associated diseases with P0CK06

3 regional properties for P0CK06

Type Name Position InterPro Accession
domain Peptidase S30, polyprotein P1, potyvirus 42 - 284 IPR002540
domain Helper-component proteinase (HC-Pro) cysteine protease (CPD) domain 618 - 740 IPR031159
domain Potyviral polyprotein protein 3 771 - 922 IPR039560

Functions

Description
EC Number
Subcellular Localization
  • Host cell junction, host plasmodesma
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
host cell plasmodesma A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.

2 GO annotations of molecular function

Name Definition
cysteine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
serine-type peptidase activity Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

2 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
transport of virus in host, cell to cell The transport of a virus between adjacent cells in a multicellular organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATYTSTIQI GSIECKLPYS PAPFGLVAGK REVSTTTDPF ASLEMQLSAR LRRQEFATIR
70 80 90 100 110 120
TSKNGTCMYR YKTDAQIARI QKKREERERE EYNFQMAASS VVSKITIAGG EPPSKLESQV
130 140 150 160 170 180
RKGVIHTTPR MRTAKTYRTP KLTEGQMNHL IKQVKQIMST KGGSVQLISK KSTHVHYKEV
190 200 210 220 230 240
LGSHRAVVCT AHMRGLRKRV DFRCDKWTVV RLQHLARTDK WTNQVRATDL RKGDSGVILS
250 260 270 280 290 300
NTNLKGHFGR SSEGLFIVRG SHEGKIYDAR SKVTQGVMDS MVQFSSAESF WEGLDGNWAQ
310 320 330 340 350 360
MRYPTDHTCV AGIPVEDCGR VAAIMTHSIL PCYKITCPTC AQQYANLPAS DLLKILHKHA
370 380 390 400 410 420
SDGLNRLGAD KDRFVHVKKF LTILEHLTEP VDLSLEIFNE VFKSIGEKQQ SPFKNLNILN
430 440 450 460 470 480
NFFLKGKENT AREWQVAQLS LLELARFQKN RTDNIKKGDI SFFRNKLSAK ANWNLYLSCD
490 500 510 520 530 540
NQLDKNANFL WGQREYHAKR FFSNYFEEID PAKGYSAYEN RLHPNGTRKL AIGNLIVPLD
550 560 570 580 590 600
LAEFRRKMKG DYKRQPGVSK KCTSSKDGNY VYPCCCTTLD DGSAVESTFY PPTKKHLVIG
610 620 630 640 650 660
NSGDQKYVDL PKGNSEMLYI ARQGFCYINI FLAMLINISE EDAKDFTKKV RDMCVPKLGT
670 680 690 700 710 720
WPTMMDLATT CAQMKIFYPD VHDAELPRIL VDHETQTCHV VDSFGSQTTG YHILKASSVS
730 740 750 760 770 780
QLILFANDEL ESDIKHYRVG GIPNACPELG STISPFREGG VIMSESAALK LLLKGIFRPK
790 800 810 820 830 840
VMRQLLLDEP YLLILSILSP GILMAMYNNG IFELAVKLWI NEKQSIAMIA SLLSALALRV
850 860 870 880 890 900
SAAETLVAQR IIIDTAATDL LDATCDGFNL HLTYPTALMV LQVVKNRNEC DDTLFKAGFP
910 920 930 940 950 960
SYNTSVVQIM EKKLSKSLER CLERFNLAGK IIRNMVLIQS KTLYHSVHKT HRKGRFERVI
970 980
QHITTSILGP RCPGGQRHCL RIERAI