Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0CI40
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0CI40-F1 | Predicted | AlphaFoldDB |
1 variants for P0CI40
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 240 | I>V | strain: SK1 [UniProt] | No |
No associated diseases with P0CI40
6 regional properties for P0CI40
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | EF-hand domain | 11 - 78 | IPR002048-1 |
| domain | EF-hand domain | 80 - 115 | IPR002048-2 |
| repeat | Mitochondrial substrate/solute carrier | 225 - 335 | IPR018108-1 |
| repeat | Mitochondrial substrate/solute carrier | 345 - 436 | IPR018108-2 |
| repeat | Mitochondrial substrate/solute carrier | 452 - 543 | IPR018108-3 |
| binding_site | EF-Hand 1, calcium-binding site | 93 - 105 | IPR018247 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| mitochondrial inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLLKNCETDK | QRDIRYACLF | KELDVKGNGQ | VTLDNLISAF | EKNDHPLKGN | DEAIKMLFTA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MDVNKDSVVD | LSDFKKYASN | AESQIWNGFQ | RIDLDHDGKI | GINEINRYLS | DLDNQSICNN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ELNHELSNEK | MNKFSRFFEW | AFPKRKANIA | LRGQASHKKN | TDNDRSKKTT | DSDLYVTYDQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| WRDFLLLVPR | KQGSRLHTAY | SYFYLFNEDV | DLSSEGDVTL | INDFIRGFGF | FIAGGISGVI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SRTCTAPFDR | LKVFLIARTD | LSSILLNSKT | DLLAKNPNAD | INKISSPLAK | AVKSLYRQGG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IKAFYVGNGL | NVIKVFPESS | IKFGSFEVTK | KIMTKLEGCR | DTKDLSKFST | YIAGGLAGMA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AQFSVYPIDT | LKFRVQCAPL | DTKLKGNNLL | FQTAKDMFRE | GGLRLFYRGV | TVGIVGIFPY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AALDLGTFSA | LKKWYIAKQA | KTLNLPQDQV | TLSNLVVLPM | GAFSGTVGAS | VVYPINLLRT |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RLQAQGTYAH | PYVYNGFKDV | LLKTLEREGY | QGLFKGLVPT | LAKVCPAVSI | SYLCYENLKK |
| FMNLE |