P0C959

PR
Gene name
AFUA_2G09030
Protein name
Dipeptidyl-peptidase 5
Names
Dipeptidyl-peptidase V, DPP V, DppV
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_2G09030
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0C959

Entry ID Method Resolution Chain Position Source
AF-P0C959-F1 Predicted AlphaFoldDB

No variants for P0C959

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0C959

No associated diseases with P0C959

2 regional properties for P0C959

Type Name Position InterPro Accession
domain Peptidase S9, prolyl oligopeptidase, catalytic domain 488 - 699 IPR001375
repeat WD40-like beta propeller 288 - 309 IPR011659

Functions

Description
EC Number
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

2 GO annotations of molecular function

Name Definition
peptidase activity Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
serine-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGAFRWLSIA AAASTALALT PEQLITAPRR SEAIPDPSGK VAVFSTSQYS FETHKRTSWW
70 80 90 100 110 120
SLLDLKTGQT KVLTNDSSVS EIVWLSDDSI LYVNSTNADI PGGVELWVTQ ASSFAKGYKA
130 140 150 160 170 180
ASLPASFSGL KTAKTKSGDI RFVAYGQSYP NGTAYNEELA TAPLSSARIY DSIYVRHWDY
190 200 210 220 230 240
WLSTTFNAVF SGTLKKGHGK NGYSLDGELK NLVSPVKNAE SPYPPFGGAS DYDLSPDGKW
250 260 270 280 290 300
VAFKSKAPEL PKANFTTSYI YLVPHDASET ARPINGPDSP GTPKGIKGDS SSPVFSPNGD
310 320 330 340 350 360
KLAYFQMRDE TYESDRRVLY VYSLGSKKTI PSVAGDWDRS PDSVKWTPDG KTLIVGSEDL
370 380 390 400 410 420
GRTRLFSLPA NAKDDYKPKN FTDGGSASAY YFLPDSSLLV TGSALWTNWN VYTAKPEKGV
430 440 450 460 470 480
IKKIASANEI DPELKGLGPS DISEFYFQGN FTDIHAWVIY PENFDKSKKY PLIFFIHGGP
490 500 510 520 530 540
QGNWADGWST RWNPKAWADQ GYVVVAPNPT GSTGFGQALT DAIQNNWGGA PYDDLVKCWE
550 560 570 580 590 600
YVHENLDYVD TDHGVAAGAS YGGFMINWIQ GSPLGRKFKA LVSHDGTFVA DAKVSTEELW
610 620 630 640 650 660
FMQREFNGTF WDARDNYRRW DPSAPERILQ FATPMLVIHS DKDYRLPVAE GLSLFNVLQE
670 680 690 700 710 720
RGVPSRFLNF PDENHWVVNP ENSLVWHQQA LGWINKYSGV EKSNPNAVSL EDTVVPVVNY
N