P0C934

PR
Gene name
gdh (PG_1232)
Protein name
NAD-specific glutamate dehydrogenase
Names
NAD-GDH, Surface-associated protein PGAG1
Species
Porphyromonas gingivalis (strain ATCC BAA-308 / W83)
KEGG Pathway
pgi:PG_1232
EC number
1.4.1.2: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-42 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0C934

Entry ID Method Resolution Chain Position Source
AF-P0C934-F1 Predicted AlphaFoldDB

No variants for P0C934

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0C934

No associated diseases with P0C934

4 regional properties for P0C934

Type Name Position InterPro Accession
domain Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal 198 - 443 IPR006096
domain Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain 53 - 181 IPR006097
active_site Leu/Phe/Val dehydrogenases active site 118 - 131 IPR033524
domain NAD(P) binding domain of glutamate dehydrogenase 191 - 444 IPR033922

Functions

Description
EC Number 1.4.1.2 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cell surface
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cell surface The external part of the cell wall and/or plasma membrane.

1 GO annotations of molecular function

Name Definition
glutamate dehydrogenase (NAD+) activity Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.

1 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTQEIMTML EAKHPGESEF LQAVKEVLLS VEEVYNQHPE FEKNGIIERI VEPDRVFTFR
70 80 90 100 110 120
VPWVDDQGKV QVNIGYRVQF NNAIGPYKGG IRFHPSVNLS ILKFLGFEQM FKNALTTLPM
130 140 150 160 170 180
GGGKGGADFS PKGKSEAEIM RFCQSFMTEL WRNIGPDTDI PAGDIGVGGR EVGYMFGMYK
190 200 210 220 230 240
KLAREHTGTL TGKGFEFGGS RLRPESTGFG AVYFVQNMCK QNGVDYKGKT LAISGFGNVA
250 260 270 280 290 300
WGVAQKATEL GIKVVTISGP DGYVYDPDGI NTPEKFRCML DLRDSGNDVV SDYVKRFPNA
310 320 330 340 350 360
QFFPGKKPWE QKVDFAMPCA TQNEMNLEDA KTLHKNGVTL VAETSNMGCT AEASEYYVAN
370 380 390 400 410 420
KMLFAPGKAV NAGGVSCSGL EMTQNAMHLV WTNEEVDKWL HQIMQDIHEQ CVTYGKDGNY
430 440
IDYVKGANIA GFMKVAKAMV AQGVC