P0C8H0

PR
Gene name
Ken-052
Protein name
Probable helicase A859L
Names
Species
African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

539-616 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P0C8H0

Entry ID Method Resolution Chain Position Source

No variants for P0C8H0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0C8H0

No associated diseases with P0C8H0

4 regional properties for P0C8H0

Type Name Position InterPro Accession
domain Helicase, C-terminal 394 - 553 IPR001650
domain Helicase/UvrB, N-terminal 165 - 332 IPR006935
domain Helicase superfamily 1/2, ATP-binding domain 162 - 361 IPR014001
domain Bacteriophage T5, Orf172 DNA-binding 5 - 81 IPR018306

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MCAGFYVAVH PWLETQSLHK VGHTGNLAAR LHDGSYTTCF TDEWRYCFTL ETPTKKDAQK
70 80 90 100 110 120
IEAGVLYCAQ FFRVKNKELL CLLPEKIKQL AEDVANCLNI SYTLCDAPTY EMNDSTIVVE
130 140 150 160 170 180
PSSPSDPLIS KEKLRHLVIT PVEDEDRFAD DVLFFSTGET RTTIEDRLYQ REAANMGYQE
190 200 210 220 230 240
LQRSGRAILQ MACRCGKTRV AYLILSNYLQ GKVLYLVPGL SLLRQTLEKL YLYGISLKNV
250 260 270 280 290 300
MLVGSDQTRI VLNHDTIEMT TNPVIIVKRI QEASSLLVIA TYQSSTLLVD DFDLIISDEC
310 320 330 340 350 360
HRICGEWETR PFTHVLLNFK KGHRLFLTAT PRYDTPLSMK NRELFGGVAF RYYLREGIEA
370 380 390 400 410 420
GYVNDFELQM VAAPKLAHQL SNREETTKQI IVKQIIMALA YLKTNVRSPK MLVFTRDIKQ
430 440 450 460 470 480
AKELYAELVD LGVYALIAHS TLPRQVILKT FTEFCSSKEP VILLNCRLFQ EGVEVPELNA
490 500 510 520 530 540
VFFAAPRHSP RDIIQSICRP LNKQVQKPHA TIFLPLEVNT ENVCLDKFSS IIPFADALAS
550 560 570 580 590 600
EDPRFYEHLL NPSEVAYPIN WIGAHGSVAE LLQLARHAIR YGTQGKIDRL TRSERLPWKA
610 620 630 640 650 660
AFAELKRTVE ICCRYPKIND GFHFGGATLR FDTWYKWVIK SYLQYKNNEP SSLEPYQVLD
670 680 690 700 710 720
LESLQDWTTR GVGGPYPWEE SMAFLETWLA QNKGELVAID IHQGGWIGLD ATPMERLSGV
730 740 750 760 770 780
LTTVSQRDGR SYGKNRKLRP KKGFMIPPQQ AKDLDRIFGK HNLKWRKDRD NGFLKEDEHG
790 800 810 820 830 840
NYTGEPTCIQ EAYQTFKEYV KTNPEYIEKY WPGYAKGKHK HQELPHIWES GLAPPRYKAF
850
KDGNKRLIQR SPKKKDVKN