P0C8G6

PR
Gene name
Protein name
Perivitellin-2 67 kDa subunit
Names
PcPV2 67 kDa subunit, PcPV2-67, PV2 MACPF subunit
Species
Pomacea canaliculata (Golden apple snail)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

214-289 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0C8G6

Entry ID Method Resolution Chain Position Source
AF-P0C8G6-F1 Predicted AlphaFoldDB

No variants for P0C8G6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0C8G6

No associated diseases with P0C8G6

2 regional properties for P0C8G6

Type Name Position InterPro Accession
conserved_site Membrane attack complex component/perforin domain, conserved site 195 - 206 IPR020863
domain Membrane attack complex component/perforin (MACPF) domain 23 - 340 IPR020864

Functions

Description
EC Number
Subcellular Localization
  • Secreted
  • Target cell membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
other organism cell membrane The cell membrane of a secondary organism with which the first organism is interacting.

2 GO annotations of molecular function

Name Definition
nutrient reservoir activity Functions in the storage of nutritious substrates.
toxin activity Interacting selectively with one or more biological molecules in another (target) organism, initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQLRWWVVS QLLLLIVVCI LDHSEGARVC PKIVPGLDKL RVGVDITKLD LLPLFDLGDN
70 80 90 100 110 120
GFRSAVADYT CDRGQTTVVD GESFDVPDQV DSVVIESSGQ QTSSVTTIKS ESQISQALSI
130 140 150 160 170 180
SAGISVDTAK AGFSSSASYA EMQEAITKYG RTVSQMSAVY TTCSANLSPN LLLGQNPLQT
190 200 210 220 230 240
LSRLPSDFTA DTEGYYDFIK TYGTHYFNKG KLGGMFLFTS ETDMSYFQNK NSQQVEANIK
250 260 270 280 290 300
ATFASILSTE TGGSSDQSKE VIEFKESSLI TAKFFGGRTN LAADGLTKWQ PTIAKLPYFM
310 320 330 340 350 360
SGTLSTISSL IADTTKRASM ELAVKNYLLK AKVANLDRLT YIRLNSWTVG HNELRDLSAQ
370 380 390 400 410 420
LQNLKKKTIF SDEDEKLLQS IEDQVSVPAW FSDRTTFCFR STAVGSADQC NGQSTSTLCA
430 440 450 460 470 480
EPNRYTQQYM DKTYLGDTGC RLVWKLSTTE SSDWFKSVKV NFRWYPTWSP CACGPVGTPF
490 500 510 520 530 540
TISAPANSWT QDYLDVTNPK FGECMLQWMI EVPPTATLWA KNLEFCIDFT CGKKKQCVDA
550 560
NHWTEPYLDI SAHEACGMSW ALIAK