P0C6B7
Gene name |
Igsf6 |
Protein name |
Immunoglobulin superfamily member 6 |
Names |
IgSF6 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:80719 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0C6B7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0C6B7-F1 | Predicted | AlphaFoldDB |
15 variants for P0C6B7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs222708412 | 24 | M>V | No | EVA | |
| rs3388937601 | 59 | P>T | No | EVA | |
| rs3388928246 | 67 | W>* | No | EVA | |
| rs3388947379 | 70 | C>Y | No | EVA | |
| rs31038999 | 98 | P>R | No | EVA | |
| rs3388946240 | 143 | E>Q | No | EVA | |
| rs32664710 | 149 | E>K | No | EVA | |
| rs262400577 | 152 | S>G | No | EVA | |
| rs3388947408 | 156 | V>M | No | EVA | |
| rs238376800 | 168 | V>L | No | EVA | |
| rs3388928315 | 195 | S>C | No | EVA | |
| rs3388916812 | 206 | E>K | No | EVA | |
| rs3388949025 | 211 | R>S | No | EVA | |
| rs3388900935 | 234 | P>A | No | EVA | |
| rs3412914037 | 237 | A>T | No | EVA |
No associated diseases with P0C6B7
1 regional properties for P0C6B7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Immunoglobulin-like domain | 13 - 134 | IPR007110 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| O95976 | IGSF6 | Immunoglobulin superfamily member 6 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGPVSARRSR | LRPEISLILF | QVGMVGACTV | YVLQPGYLEV | DYGSDAVTME | CNFSTVGCPP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VPPKSLWFRC | GTHQPEALCL | DGCRNEADKF | TVKETLDPDQ | VFLTVNRLSP | NDSAIYICGI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AFPNELSPSA | KHVGKGTTLV | VRERLFSKEV | RSFLIVLLAL | LSVYITGVCV | TFIVLFKSKS |
| 190 | 200 | 210 | 220 | 230 | |
| NGPRSRETKG | SKKKSARRIF | QEIAQELYHK | RYVETSHLPE | QEGTDENRKA | LPNPGRA |