P0AFY9

PR
Gene name
seqA
Protein name
Negative modulator of initiation of replication
Names
Species
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
KEGG Pathway
ecc:c0774
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-90 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0AFY9

Entry ID Method Resolution Chain Position Source
AF-P0AFY9-F1 Predicted AlphaFoldDB

No variants for P0AFY9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0AFY9

No associated diseases with P0AFY9

3 regional properties for P0AFY9

Type Name Position InterPro Accession
domain Phenylalanyl-tRNA synthetase 124 - 353 IPR002319
domain Aminoacyl-tRNA synthetase, class II 207 - 351 IPR006195
domain O-phosphoserine--tRNA(Cys) ligase, C-terminal domain 436 - 467 IPR041590

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
negative regulation of DNA-templated DNA replication initiation Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTIEVDDEL YSYIASHTKH IGESASDILR RMLKFSAASQ PAAPVTKEVR VASPAIVEAK
70 80 90 100 110 120
PVKTIKDKVR AMRELLLSDE YAEQKRAVNR FMLLLSTLYS LDAQAFAEAT ESLHGRTRVY
130 140 150 160 170 180
FAADEQTLLK NGNQTKPKHV PGTPYWVITN TNTGRKCSMI EHIMQSMQFP AELIEKVCGT
I