P0AFX9

PR
Gene name
rseB (b2571, JW2555)
Protein name
Sigma-E factor regulatory protein RseB
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b2571
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for P0AFX9

Entry ID Method Resolution Chain Position Source
2P4B X-ray 240 A A/B/C 24-318 PDB
2V42 X-ray 275 A A/B 23-318 PDB
2V43 X-ray 237 A A/B/C 23-318 PDB
3M4W X-ray 230 A A/B/C/D 24-318 PDB
AF-P0AFX9-F1 Predicted AlphaFoldDB

No variants for P0AFX9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0AFX9

No associated diseases with P0AFX9

2 regional properties for P0AFX9

Type Name Position InterPro Accession
domain MucB/RseB, N-terminal 28 - 197 IPR033434
domain MucB/RseB, C-terminal 217 - 313 IPR033436

Functions

Description
EC Number
Subcellular Localization
  • Periplasm
  • Partially associates with the inner membrane via RseA
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
outer membrane-bounded periplasmic space The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
sigma factor antagonist complex A protein complex which is capable of sigma factor antagonist activity.

3 GO annotations of molecular function

Name Definition
antisigma factor binding Binding to an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
identical protein binding Binding to an identical protein or proteins.
lipid binding Binding to a lipid.

2 GO annotations of biological process

Name Definition
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKQLWFAMSL VTGSLLFSAN ASATPASGAL LQQMNLASQS LNYELSFISI NKQGVESLRY
70 80 90 100 110 120
RHARLDNRPL AQLLQMDGPR REVVQRGNEI SYFEPGLEPF TLNGDYIVDS LPSLIYTDFK
130 140 150 160 170 180
RLSPYYDFIS VGRTRIADRL CEVIRVVARD GTRYSYIVWM DTESKLPMRV DLLDRDGETL
190 200 210 220 230 240
EQFRVIAFNV NQDISSSMQT LAKANLPPLL SVPVGEKAKF SWTPTWLPQG FSEVSSSRRP
250 260 270 280 290 300
LPTMDNMPIE SRLYSDGLFS FSVNVNRATP SSTDQMLRTG RRTVSTSVRD NAEITIVGEL
310
PPQTAKRIAE NIKFGAAQ