P0AFA5

PR
Gene name
nfrB (b0569, JW0558)
Protein name
Bacteriophage adsorption protein B
Names
Bacteriophage N4 adsorption protein B
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b0569
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

595-668 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0AFA5

Entry ID Method Resolution Chain Position Source
AF-P0AFA5-F1 Predicted AlphaFoldDB

No variants for P0AFA5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0AFA5

No associated diseases with P0AFA5

1 regional properties for P0AFA5

Type Name Position InterPro Accession
domain Cation/H+ exchanger 7 - 412 IPR006153

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
type II protein secretion system complex A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
protein secretion by the type II secretion system The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDWLLDVFAT WLYGLKVIAI TLAVIMFISG LDDFFIDVVY WVRRIKRKLS VYRRYPRMSY
70 80 90 100 110 120
RELYKPDEKP LAIMVPAWNE TGVIGNMAEL AATTLDYENY HIFVGTYPND PDTQRDVDEV
130 140 150 160 170 180
CARFPNVHKV VCARPGPTSK ADCLNNVLDA ITQFERSANF AFAGFILHDA EDVISPMELR
190 200 210 220 230 240
LFNYLVERKD LIQIPVYPFE REWTHFTSMT YIDEFSELHG KDVPVREALA GQVPSAGVGT
250 260 270 280 290 300
CFSRRAVTAL LADGDGIAFD VQSLTEDYDI GFRLKEKGMT EIFVRFPVVD EAKEREQRKF
310 320 330 340 350 360
LQHARTSNMI CVREYFPDTF STAVRQKSRW IIGIVFQGFK THKWTSSLTL NYFLWRDRKG
370 380 390 400 410 420
AISNFVSFLA MLVMIQLLLL LAYESLWPDA WHFLSIFSGS AWLMTLLWLN FGLMVNRIVQ
430 440 450 460 470 480
RVIFVTGYYG LTQGLLSVLR LFWGNLINFM ANWRALKQVL QHGDPRRVAW DKTTHDFPSV
490 500 510 520 530 540
TGDTRSLRPL GQILLENQVI TEEQLDTALR NRVEGLRLGG SMLMQGLISA EQLAQALAEQ
550 560 570 580 590 600
NGVAWESIDA WQIPSSLIAE MPASVALHYA VLPLRLENDE LIVGSEDGID PVSLAALTRK
610 620 630 640 650 660
VGRKVRYVIV LRGQIVTGLR HWYARRRGHD PRAMLYNAVQ HQWLTEQQAG EIWRQYVPHQ
670 680 690 700 710 720
FLFAEILTTL GHINRSAINV LLLRHERSSL PLGKFLVTEG VISQETLDRV LTIQRELQVS
730 740
MQSLLLKAGL NTEQVAQLES ENEGE