P0AF98
Gene name |
lptF (yjgP, b4261, JW4218) |
Protein name |
Lipopolysaccharide export system permease protein LptF |
Names |
|
Species |
Escherichia coli (strain K12) |
KEGG Pathway |
eco:b4261 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
5 structures for P0AF98
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 6MHU | EM | 400 A | F | 1-366 | PDB |
| 6MHZ | EM | 410 A | F | 1-366 | PDB |
| 6MI7 | EM | 420 A | F | 1-366 | PDB |
| 6MI8 | EM | 430 A | F | 1-366 | PDB |
| AF-P0AF98-F1 | Predicted | AlphaFoldDB |
No variants for P0AF98
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0AF98 | |||||
No associated diseases with P0AF98
No regional properties for P0AF98
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P0AF98 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| ATP-binding cassette (ABC) transporter complex | A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| transporter complex | A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| Gram-negative-bacterium-type cell outer membrane assembly | The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures. |
| lipopolysaccharide transport | The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide. |
| transmembrane transport | The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIIIRYLVRE | TLKSQLAILF | ILLLIFFCQK | LVRILGAAVD | GDIPANLVLS | LLGLGVPEMA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QLILPLSLFL | GLLMTLGKLY | TESEITVMHA | CGLSKAVLVK | AAMILAVFTA | IVAAVNVMWA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GPWSSRHQDE | VLAEAKANPG | MAALAQGQFQ | QATNGSSVLF | IESVDGSDFK | DVFLAQIRPK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GNARPSVVVA | DSGHLTQLRD | GSQVVTLNQG | TRFEGTALLR | DFRITDFQDY | QAIIGHQAVA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LDPNDTDQMD | MRTLWNTDTD | RARAELNWRI | TLVFTVFMMA | LMVVPLSVVN | PRQGRVLSML |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PAMLLYLLFF | LIQTSLKSNG | GKGKLDPTLW | MWTVNLIYLA | LAIVLNLWDT | VPVRRLRASF |
| SRKGAV |