P0AEY4
Gene name |
mazG (Z4096, ECs3641) |
Protein name |
Nucleoside triphosphate pyrophosphohydrolase |
Names |
NTP-PPase |
Species |
Escherichia coli O157:H7 |
KEGG Pathway |
ecs:ECs_3641 |
EC number |
3.6.1.8: In phosphorus-containing anhydrides |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0AEY4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0AEY4-F1 | Predicted | AlphaFoldDB |
No variants for P0AEY4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0AEY4 | |||||
No associated diseases with P0AEY4
6 regional properties for P0AEY4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Translational (tr)-type GTP-binding domain | 403 - 572 | IPR000795 |
| domain | Small GTP-binding protein domain | 405 - 562 | IPR005225 |
| domain | Translation initiation factor IF-2, N-terminal | 327 - 377 | IPR006847 |
| domain | Initiation factor 2 associated domain, bacterial | 70 - 105 | IPR013575 |
| domain | Translation initiation factor IF- 2, domain 3 | 680 - 794 | IPR023115 |
| domain | Translation initiation factor IF-2, domain II | 578 - 672 | IPR044145 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.6.1.8 | In phosphorus-containing anhydrides |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP diphosphatase activity | Catalysis of the reaction: ATP + H2O = AMP + H+ + diphosphate. |
| metal ion binding | Binding to a metal ion. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNQIDRLLTI | MQRLRDPENG | CPWDKEQTFA | TIAPYTLEET | YEVLDAIARE | DFDDLRGELG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DLLFQVVFYA | QMAQEEGRFD | FNDICAAISD | KLERRHPHVF | ADSSAENSSE | VLARWEQIKT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EERAQKAQHS | ALDDIPRSLP | ALMRAQKIQK | RCANVGFDWT | TLGPVVDKVY | EEIDEVMYEA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RQAVVDQAKL | EEEMGDLLFA | TVNLARHLGT | KAEIALQKAN | EKFERRFREV | ERIVAARGLE |
| 250 | 260 | ||||
| MTGVDLETME | EVWQQVKRQE | IDL |