P0AEJ3
Gene name |
entC |
Protein name |
Isochorismate synthase EntC |
Names |
Isochorismate mutase |
Species |
Escherichia coli O157:H7 |
KEGG Pathway |
ecs:ECs_0632 |
EC number |
5.4.4.2: Transferring hydroxy groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0AEJ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0AEJ3-F1 | Predicted | AlphaFoldDB |
No variants for P0AEJ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0AEJ3 | |||||
No associated diseases with P0AEJ3
1 regional properties for P0AEJ3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Chorismate-utilising enzyme, C-terminal | 126 - 380 | IPR015890 |
Functions
| Description | ||
|---|---|---|
| EC Number | 5.4.4.2 | Transferring hydroxy groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| isochorismate synthase activity | Catalysis of the reaction: chorismate = isochorismate. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| enterobactin biosynthetic process | The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDTSLAEEVQ | QTMATLAPNR | FFFMSPYRSF | TTSGCFARFD | EPAVNGDSPD | SPFQQKLAAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FADAKAQGIK | NPVMVGAIPF | DPRQPSSLYI | PESWQSFSRQ | EKQASARRFT | RSQSLNVVER |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QAIPEQTTFE | QMVARAAALT | ATPQVDKVVL | SRLIDITTDA | AIDSGVLLER | LIAQNPVSYN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FHVPLADGGV | LLGASPELLL | RKDGERFSSI | PLAGSARRQP | DEVLDREAGN | RLLASEKDRH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EHELVTQAMK | EVLRERSSEL | HVPSSPQLIT | TPTLWHLATP | FEGKANSQEN | ALTLACLLHP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| TPALSGFPHQ | AATQVIAELE | PFDRELFGGI | VGWCDSEGNG | EWVVTIRCAK | LRENQVRLFA |
| 370 | 380 | 390 | |||
| GAGIVPASSP | LGEWRETGVK | LSTMLNVFGL | H |