P0AE89

PR
Gene name
cpxR (Z5457, ECs4838)
Protein name
Transcriptional regulatory protein CpxR
Names
Species
Escherichia coli O157:H7
KEGG Pathway
ecs:ECs_4838
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

89-232 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0AE89

Entry ID Method Resolution Chain Position Source
AF-P0AE89-F1 Predicted AlphaFoldDB

No variants for P0AE89

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0AE89

No associated diseases with P0AE89

2 regional properties for P0AE89

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 2 - 115 IPR001789
domain OmpR/PhoB-type DNA-binding domain 131 - 230 IPR001867

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

2 GO annotations of biological process

Name Definition
phosphorelay signal transduction system A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKILLVDDD RELTSLLKEL LEMEGFNVIV AHDGEQALDL LDDSIDLLLL DVMMPKKNGI
70 80 90 100 110 120
DTLKALRQTH QTPVIMLTAR GSELDRVLGL ELGADDYLPK PFNDRELVAR IRAILRRSHW
130 140 150 160 170 180
SEQQQNNDNG SPTLEVDALV LNPGRQEASF DGQTLELTGT EFTLLYLLAQ HLGQVVSREH
190 200 210 220 230
LSQEVLGKRL TPFDRAIDMH ISNLRRKLPD RKDGHPWFKT LRGRGYLMVS AS