P0ACV3

PR
Gene name
lpxP
Protein name
Lipid A biosynthesis palmitoleoyltransferase
Names
Kdo(2)-lipid IV(A) palmitoleoyltransferase
Species
Shigella flexneri
KEGG Pathway
sfx:S2582
EC number
2.3.1.242: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

30-101 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0ACV3

Entry ID Method Resolution Chain Position Source
AF-P0ACV3-F1 Predicted AlphaFoldDB

No variants for P0ACV3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0ACV3

No associated diseases with P0ACV3

No regional properties for P0ACV3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P0ACV3

Functions

Description
EC Number 2.3.1.242 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cell inner membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity Catalysis of the reaction: a palmitoleoyl- + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-

4 GO annotations of biological process

Name Definition
Kdo2-lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.
lipid A biosynthetic process The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common.
lipopolysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFPQCKFSRE FLHPRYWLTW FGLGVLWLWV QLPYPVLCFL GTRIGAMARP FLKRRESIAR
70 80 90 100 110 120
KNLELCFPQH SAEEREKMIA ENFRSLGMAL VETGMAWFWP DSRVRKWFDV EGLDNLKRAQ
130 140 150 160 170 180
MQNRGVMVVG VHFMSLELGG RVMGLCQPMM ATYRPHNNQL MEWVQTRGRM RSNKAMIGRN
190 200 210 220 230 240
NLRGIVGALK KGEAVWFAPD QDYGRKGSSF APFFAVENVA TTNGTYVLSR LSGAAMLTVT
250 260 270 280 290 300
MVRKADYSGY RLFITPEMEG YPTDENQAAA YMNKIIEKEI MRAPEQYLWI HRRFKTRPVG
ESSLYI