P0ACV1
Gene name |
lpxL |
Protein name |
Lipid A biosynthesis lauroyltransferase |
Names |
Kdo(2)-lipid IV(A) lauroyltransferase |
Species |
Escherichia coli O157:H7 |
KEGG Pathway |
ecs:ECs_1432 |
EC number |
2.3.1.241: Transferring groups other than amino-acyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0ACV1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0ACV1-F1 | Predicted | AlphaFoldDB |
No variants for P0ACV1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0ACV1 | |||||
No associated diseases with P0ACV1
No regional properties for P0ACV1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P0ACV1 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.1.241 | Transferring groups other than amino-acyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| lauroyltransferase activity | Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| Kdo2-lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component. |
| lipid A biosynthetic process | The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of four to six fatty acyl chains linked to two glucosamine residues. Further modifications of the backbone are common. |
| lipopolysaccharide biosynthetic process | The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTNLPKFSTA | LLHPRYWLTW | LGIGVLWLVV | QLPYPVIYRL | GCGLGKLALR | FMKRRAKIVH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RNLELCFPEM | SEQERRKMVV | KNFESVGMGL | METGMAWFWP | DRRIARWTEV | IGMEHIRDVQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AQKRGILLVG | IHFLTLELGA | RQFGMQEPGI | GVYRPNDNPL | IDWLQTWGRL | RSNKSMLDRK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DLKGMIKALK | KGEVVWYAPD | HDYGPRSSVF | VPLFAVEQAA | TTTGTWMLAR | MSGACLVPFV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PRRKPDGKGY | QLIMLPPECS | PPLDDAETTA | AWMNKVVEKC | IMMAPEQYMW | LHRRFKTRPE |
| GVPSRY |