P0ACS8

PR
Gene name
rpiR (c5095)
Protein name
HTH-type transcriptional regulator RpiR
Names
Als operon repressor
Species
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
KEGG Pathway
ecc:c5095
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-135 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0ACS8

Entry ID Method Resolution Chain Position Source
AF-P0ACS8-F1 Predicted AlphaFoldDB

No variants for P0ACS8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0ACS8

No associated diseases with P0ACS8

2 regional properties for P0ACS8

Type Name Position InterPro Accession
active_site Beta-lactamase, class-A active site 82 - 97 IPR023650
domain Beta-lactamase class A, catalytic domain 62 - 276 IPR045155

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
carbohydrate derivative binding Binding to a carbohydrate derivative.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

1 GO annotations of biological process

Name Definition
carbohydrate derivative metabolic process The chemical reactions and pathways involving carbohydrate derivative.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQSEFDSAL PNGIGLAPYL RMKQEGMTEN ESRIVEWLLK PGNLSCAPAI KDVAEALAVS
70 80 90 100 110 120
EAMIVKVSKL LGFSGFRNLR SALEDYFSQS EQVLPSELAF DEAPQDVVNK VFNITLRTIM
130 140 150 160 170 180
EGQSIVNVDE IHRAARFFYQ ARQRDLYGAG GSNAICADVQ HKFLRIGVRC QAYPDAHIMM
190 200 210 220 230 240
MSASLLQEGD VVLVVTHSGR TSDVKAAVEL AKKNGAKIIC ITHSYHSPIA KLADYIICSP
250 260 270 280 290
APETPLLGRN ASARILQLTL LDAFFVSVAQ LNIEQANINM QKTGAIVDFF SPGALK