P0ABV6

PR
Gene name
tolR
Protein name
Tol-Pal system protein TolR
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b0738
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-131 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P0ABV6

Entry ID Method Resolution Chain Position Source
5BY4 X-ray 170 A A 36-142 PDB
8ODT EM 420 A F/G 1-142 PDB
AF-P0ABV6-F1 Predicted AlphaFoldDB

No variants for P0ABV6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0ABV6

No associated diseases with P0ABV6

No regional properties for P0ABV6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P0ABV6

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Single-pass membrane protein
  • Accumulates at cell constriction sites
  • Recruitment to the division site is dependent on FtsN activity
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
transmembrane transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.

5 GO annotations of biological process

Name Definition
bacteriocin transport The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of membrane invagination Any process that modulates the frequency, rate or extent of membrane invagination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARARGRGRR DLKSEINIVP LLDVLLVLLL IFMATAPIIT QSVEVDLPDA TESQAVSSND
70 80 90 100 110 120
NPPVIVEVSG IGQYTVVVEK DRLERLPPEQ VVAEVSSRFK ANPKTVFLIG GAKDVPYDEI
130 140
IKALNLLHSA GVKSVGLMTQ PI