P0A9W5
Gene name |
ettA |
Protein name |
Energy-dependent translational throttle protein EttA |
Names |
Translational regulatory factor EttA |
Species |
Shigella flexneri |
KEGG Pathway |
sfx:S4694 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P0A9W5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P0A9W5-F1 | Predicted | AlphaFoldDB |
No variants for P0A9W5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P0A9W5 | |||||
No associated diseases with P0A9W5
No regional properties for P0A9W5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P0A9W5 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
| ribosome binding | Binding to a ribosome. |
| rRNA binding | Binding to a ribosomal RNA. |
| tRNA binding | Binding to a transfer RNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of translational elongation | Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAQFVYTMHR | VGKVVPPKRH | ILKNISLSFF | PGAKIGVLGL | NGAGKSTLLR | IMAGIDKDIE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GEARPQPDIK | IGYLPQEPQL | NPEHTVRESI | EEAVSEVVNA | LKRLDEVYAL | YADPDADFDK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LAAEQGRLEE | IIQAHDGHNL | NVQLERAADA | LRLPDWDAKI | ANLSGGERRR | VALCRLLLEK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PDMLLLDEPT | NHLDAESVAW | LERFLHDFEG | TVVAITHDRY | FLDNVAGWIL | ELDRGEGIPW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EGNYSSWLEQ | KDQRLAQEAS | QEAARRKSIE | KELEWVRQGT | KGRQSKGKAR | LARFEELNST |
| 310 | 320 | 330 | 340 | 350 | 360 |
| EYQKRNETNE | LFIPPGPRLG | DKVLEVSNLR | KSYGDRLLID | DLSFSIPKGA | IVGIIGPNGA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GKSTLFRMIS | GQEQPDSGTI | TLGETVKLAS | VDQFRDSMDN | SKTVWEEVSG | GLDIMKIGNT |
| 430 | 440 | 450 | 460 | 470 | 480 |
| EMPSRAYVGR | FNFKGVDQGK | RVGELSGGER | GRLHLAKLLQ | VGGNMLLLDE | PTNDLDIETL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RALENALLEF | PGCAMVISHD | RWFLDRIATH | ILDYQDEGKV | EFFEGNFTEY | EEYKKRTLGA |
| 550 | |||||
| DALEPKRIKY | KRIAK |