P0A707

PR
Gene name
infC
Protein name
Translation initiation factor IF-3
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b1718
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-43 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for P0A707

Entry ID Method Resolution Chain Position Source
2IFE NMR - A 81-180 PDB
5ME0 EM 1350 A Z 38-180 PDB
5ME1 EM 1350 A Z 37-180 PDB
AF-P0A707-F1 Predicted AlphaFoldDB

No variants for P0A707

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0A707

No associated diseases with P0A707

3 regional properties for P0A707

Type Name Position InterPro Accession
conserved_site Translation initiation factor 3, conserved site 66 - 79 IPR019813
domain Translation initiation factor 3, N-terminal 15 - 84 IPR019814
domain Translation initiation factor 3, C-terminal 91 - 177 IPR019815

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

3 GO annotations of molecular function

Name Definition
ribosome binding Binding to a ribosome.
RNA binding Binding to an RNA molecule or a portion thereof.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

2 GO annotations of biological process

Name Definition
response to cold Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
ribosome disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKGGKRVQTA RPNRINGEIR AQEVRLTGLE GEQLGIVSLR EALEKAEEAG VDLVEISPNA
70 80 90 100 110 120
EPPVCRIMDY GKFLYEKSKS SKEQKKKQKV IQVKEIKFRP GTDEGDYQVK LRSLIRFLEE
130 140 150 160 170
GDKAKITLRF RGREMAHQQI GMEVLNRVKD DLQELAVVES FPTKIEGRQM IMVLAPKKKQ