P0A6Y5

PR
Gene name
hslO
Protein name
33 kDa chaperonin
Names
Heat shock protein 33, HSP33
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b3401
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

52-122 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for P0A6Y5

Entry ID Method Resolution Chain Position Source
1HW7 X-ray 220 A A 1-253 PDB
1I7F X-ray 270 A A 1-292 PDB
1XJH NMR - A 225-285 PDB
3M7M X-ray 290 A X 1-233 PDB
AF-P0A6Y5-F1 Predicted AlphaFoldDB

No variants for P0A6Y5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0A6Y5

No associated diseases with P0A6Y5

No regional properties for P0A6Y5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P0A6Y5

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
identical protein binding Binding to an identical protein or proteins.
protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process.
unfolded protein binding Binding to an unfolded protein.
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
maintenance of unfolded protein Maintaining a protein in an unfolded, soluble state.
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPQHDQLHRY LFENFAVRGE LVTVSETLQQ ILENHDYPQP VKNVLAELLV ATSLLTATLK
70 80 90 100 110 120
FDGDITVQLQ GDGPMNLAVI NGNNNQQMRG VARVQGEIPE NADLKTLVGN GYVVITITPS
130 140 150 160 170 180
EGERYQGVVG LEGDTLAACL EDYFMRSEQL PTRLFIRTGD VDGKPAAGGM LLQVMPAQNA
190 200 210 220 230 240
QQDDFDHLAT LTETIKTEEL LTLPANEVLW RLYHEEEVTV YDPQDVEFKC TCSRERCADA
250 260 270 280 290
LKTLPDEEVD SILAEDGEID MHCDYCGNHY LFNAMDIAEI RNNASPADPQ VH