P0A3M4

PR
Gene name
bla (oxa9)
Protein name
Beta-lactamase OXA-9
Names
Oxacillinase, Penicillinase
Species
Klebsiella aerogenes (Enterobacter aerogenes)
KEGG Pathway
EC number
3.5.2.6: In cyclic amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

49-124 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P0A3M4

Entry ID Method Resolution Chain Position Source
AF-P0A3M4-F1 Predicted AlphaFoldDB

No variants for P0A3M4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P0A3M4

No associated diseases with P0A3M4

2 regional properties for P0A3M4

Type Name Position InterPro Accession
domain Penicillin-binding protein, transpeptidase 42 - 244 IPR001460
active_site Beta-lactamase, class-D active site 56 - 66 IPR002137

Functions

Description
EC Number 3.5.2.6 In cyclic amides
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
beta-lactamase activity Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.
penicillin binding Binding to penicillin, an antibiotic that contains the condensed beta-lactamthiazolidine ring system.

2 GO annotations of biological process

Name Definition
antibiotic catabolic process The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKILLLHML VFVSATLPIS SVASDEVETL KCTIIADAIT GNTLYETGEC ARRVSPCSSF
70 80 90 100 110 120
KLPLAIMGFD SGILQSPKSP TWELKPEYNP SPRDRTYKQV YPALWQSDSV VWFSQQLTSR
130 140 150 160 170 180
LGVDRFTEYV KKFEYGNQDV SGDSGKHNGL TQSWLMSSLT ISPKEQIQFL LRFVAHKLPV
190 200 210 220 230 240
SEAAYDMAYA TIPQYQAAEG WAVHGKSGSG WLRDNNGKIN ESRPQGWFVG WAEKNGRQVV
250 260 270
FARLEIGKEK SDIPGGSKAR EDILVELPVL MGNK