P09786

PR
Gene name
phnB
Protein name
Anthranilate synthase component 2, pyocyanine specific
Names
AS, ASII, Anthranilate synthase beta subunit, pyocyanine specific, Anthranilate synthase, GATase component, Anthranilate synthase, glutamine amidotransferase component
Species
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
KEGG Pathway
pae:PA1002
EC number
4.1.3.27: Oxo-acid-lyases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

68-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P09786

Entry ID Method Resolution Chain Position Source
AF-P09786-F1 Predicted AlphaFoldDB

2 variants for P09786

Variant ID(s) Position Change Description Diseaes Association Provenance
148 D>ES strain: PAC174 [UniProt] No
195 R>A strain: PAC174 [UniProt] No

No associated diseases with P09786

2 regional properties for P09786

Type Name Position InterPro Accession
domain Anthranilate synthase/para-aminobenzoate synthase like domain 3 - 186 IPR006221
domain Glutamine amidotransferase 5 - 186 IPR017926

Functions

Description
EC Number 4.1.3.27 Oxo-acid-lyases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
anthranilate phosphoribosyltransferase activity Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.
anthranilate synthase activity Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.

3 GO annotations of biological process

Name Definition
glutamine metabolic process The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
phenazine biosynthetic process The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.
tryptophan biosynthetic process The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRITLLDNFD SFTYNLVEQF CLLGAEVRVM RNDTPLPTIQ AALLADGCEL LVLSPGPGRP
70 80 90 100 110 120
EDAGCMLELL AWARGRLPVL GVCLGHQALA LAAGGAVGEA RKPLHGKSTS LRFDQRHPLF
130 140 150 160 170 180
DGIADLRVAR YHSLVVSRLP EGFDCLADAD GEIMAMADPR NRQLGLQFHP ESILTTHGQR
190
LLENALLWCG ALAVRERLRA