P09580

PR
Gene name
GAL7 (KLLA0F08437g)
Protein name
Galactose-1-phosphate uridylyltransferase
Names
Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase
Species
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
KEGG Pathway
kla:KLLA0_F08437g
EC number
2.7.7.12: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-83 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P09580

Entry ID Method Resolution Chain Position Source
AF-P09580-F1 Predicted AlphaFoldDB

No variants for P09580

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P09580

No associated diseases with P09580

3 regional properties for P09580

Type Name Position InterPro Accession
domain Galactose-1-phosphate uridyl transferase, N-terminal 2 - 189 IPR005849
domain Galactose-1-phosphate uridyl transferase, C-terminal 196 - 362 IPR005850
active_site Galactose-1-phosphate uridyl transferase, class I His-active site 164 - 181 IPR019779

Functions

Description
EC Number 2.7.7.12 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
UDP-glucose:hexose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.
zinc ion binding Binding to a zinc ion (Zn).

1 GO annotations of biological process

Name Definition
galactose catabolic process via UDP-galactose The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSFDLTDHSH ARYNPLTDSW ILVSPHRAKR PWLGQQEKPG RNDAPDHDDK CYLCPGTTRA
70 80 90 100 110 120
TGEQNPDYES TYVFTNGYPA VKLEQPDPEL TVSNCDALKE RLFKLKGVKG NCYVICFSPK
130 140 150 160 170 180
HNLSFPQMAQ SEIMNVVKTW TNLFQTLEKE ALEENKPYKY LQIFENKGTA MGCSNLHPHG
190 200 210 220 230 240
QAWCLDSIPS EPAKEFDHFE KYEHQHGAHL LEDYVNLELR EKERIVCEND SFLVVVPYWA
250 260 270 280 290 300
VWPFETMVLS KRRIPSLNQF TDKEREDLAS IIRNLTIRYD NLFETSFPYS MGLHQASLNA
310 320 330 340 350 360
TEGELKAAWF HMHFYPPLLR SATVRKFLVG FELLGQPQRD LTAEQAADRL KALSGEVHYL
AKLEQEESKT