P09379

PR
Gene name
GYP7 (YALI0F31911g)
Protein name
GTPase-activating protein GYP7
Names
GAP for YPT7
Species
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
KEGG Pathway
yli:YALI0F31911g
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

48-391 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P09379

Entry ID Method Resolution Chain Position Source
AF-P09379-F1 Predicted AlphaFoldDB

No variants for P09379

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P09379

No associated diseases with P09379

2 regional properties for P09379

Type Name Position InterPro Accession
domain Rab-GAP-TBC domain 385 - 644 IPR000195
domain Small G protein signalling modulator 1/2, Rab-binding domain 20 - 151 IPR021935

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
GTPase activator activity Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.

3 GO annotations of biological process

Name Definition
activation of GTPase activity Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
regulation of vacuole fusion, non-autophagic Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
vesicle-mediated transport A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNSLWPVSVS HTQLTSINHQ VYVHPTPSSK DNIPGFLALA KPRGATTDKE ILVAWIPESK
70 80 90 100 110 120
LQESAADFES YVKVDIKESG TPASSSLNLA ETLVSPPPSS SFSSYAFSIP ISDIFSLQVK
130 140 150 160 170 180
QPSLGWWWGS ITIHTRSKED QLPPLYFHDA ESQSTIMEQK RRNKKFETFD SESGSSMFWG
190 200 210 220 230 240
GDHFIQVLSK YANLERAESD HSFLLVNPRE GDAERFGTNL TGGSEEPSQL VAGIPGRGAG
250 260 270 280 290 300
GDPVDRGAQV QKAFSDIRWG LLSNLAKVTQ LTRKVSQGVW DSSPQPVKQL LMKPEVKKIG
310 320 330 340 350 360
DDFDSARIYL AKWALSVAEE SQRAKLKVLF DDELRELVSD EGFELIDAEN NPQRRNEVSL
370 380 390 400 410 420
AEWNAFFDYN GRLIVTVNEV KERIFHGGLA PAVRPEGWLF LLGVYPWDST AAERKELVSK
430 440 450 460 470 480
LRVDYNRLKK EWWVQEDKER DDFWRDQLSR IEKDVHRTDR NITFFAECDA KKDGDDDNYD
490 500 510 520 530 540
KDEFGFSSQI NSNIHLIQLR DMLITYNQHN KNLGYVQGMS DLLSPLYVVL QDDTLAFWAF
550 560 570 580 590 600
SAFMERMERN YLRDQSGMRN QLLCLDHLVQ FMLPSLYKHL EKTESTNLFF FFRMLLVWFK
610 620 630 640 650 660
RELLWDDVLR LWEVLWTDYL SSQFVLFVCL AILDKHKDVM IDHLAGFDEI LKYMNELSMT
670 680 690 700 710 720
IDLDELLVRA ELLFYRFRRT VELIDRKNED RRNSADGSEP VSITEDLREL LSRKVIVVRE
GERPEGVMGG