Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P09130
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 3D8A | X-ray | 255 A | S/T/U/V/W/X/Y/Z | 708-717 | PDB |
| AF-P09130-F1 | Predicted | AlphaFoldDB |
1 variants for P09130
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 396 | P>L | traD39; temperature-sensitive [UniProt] | No |
No associated diseases with P09130
1 regional properties for P09130
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal | 79 - 236 | IPR018955 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| unidirectional conjugation | The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells. Some or all of the chromosome(s) of the donor cell is transferred into the recipient cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFNAKDMTQ | GGQIASMRIR | MFSQIANIML | YCLFIFFWIL | VGLVLWIKIS | WQTFVNGCIY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| WWCTTLEGMR | DLIKSQPVYE | IQYYGKTFRM | NAAQVLHDKY | MIWCSEQLWS | AFVLAAVVAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VICLITFFVV | SWILGRQGKQ | QSENEVTGGR | QLTDNPKDVA | RMLKKDGKDS | DIRIGDLPII |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RDSEIQNFCL | HGTVGAGKSE | VIRRLANYAR | QRGDMVVIYD | RSGEFVKSYY | DPSIDKILNP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LDARCAAWDL | WKECLTQPDF | DNTANTLIPM | GTKEDPFWQG | SGRTIFAEAA | YLMRNDPNRS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YSKLVDTLLS | IKIEKLRTYL | RNSPAANLVE | EKIEKTAISI | RAVLTNYVKA | IRYLQGIEHN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GEPFTIRDWM | RGVREDQKNG | WLFISSNADT | HASLKPVISM | WLSIAIRGLL | AMGENRNRRV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| WFFCDELPTL | HKLPDLVEIL | PEARKFGGCY | VFGIQSYAQL | EDIYGEKAAA | SLFDVMNTRA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| FFRSPSHKIA | EFAAGEIGEK | EHLKASEQYS | YGADPVRDGV | STGKDMERQT | LVSYSDIQSL |
| 550 | 560 | 570 | 580 | 590 | 600 |
| PDLTCYVTLP | GPYPAVKLSL | KYQTRPKVAP | EFIPRDINPE | MENRLSAVLA | AREAEGRQMA |
| 610 | 620 | 630 | 640 | 650 | 660 |
| SLFEPDVPEV | VSGEDVTQAE | QPQQPVSPAI | NDKKSDSGVN | VPAGGIEQEL | KMKPEEEMEQ |
| 670 | 680 | 690 | 700 | 710 | |
| QLPPGISESG | EVVDMAAYEA | WQQENHPDIQ | QQMQRREEVN | INVHRERGED | VEPGDDF |