P09114

PR
Gene name
ALS (SURB)
Protein name
Acetolactate synthase 2, chloroplastic
Names
ALS II, Acetohydroxy-acid synthase II, Acetolactate synthase II
Species
Nicotiana tabacum (Common tobacco)
KEGG Pathway
EC number
2.2.1.6: Transketolases and transaldolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-53 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P09114

Entry ID Method Resolution Chain Position Source
AF-P09114-F1 Predicted AlphaFoldDB

No variants for P09114

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P09114

No associated diseases with P09114

1 regional properties for P09114

Type Name Position InterPro Accession
active_site Adenosine/AMP deaminase active site 659 - 665 IPR006650

Functions

Description
EC Number 2.2.1.6 Transketolases and transaldolases
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

4 GO annotations of molecular function

Name Definition
acetolactate synthase activity Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.
flavin adenine dinucleotide binding Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
magnesium ion binding Binding to a magnesium (Mg) ion.
thiamine pyrophosphate binding Binding to thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.

3 GO annotations of biological process

Name Definition
isoleucine biosynthetic process The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
response to herbicide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.
valine biosynthetic process The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAAAAAPSP SFSKTLSSSS SKSSTLLPRS TFPFPHHPHK TTPPPLHLTP THIHSQRRRF
70 80 90 100 110 120
TISNVISTTQ KVSETQKAET FVSRFAPDEP RKGSDVLVEA LEREGVTDVF AYPGGASMEI
130 140 150 160 170 180
HQALTRSSII RNVLPRHEQG GVFAAEGYAR ATGFPGVCIA TSGPGATNLV SGLADALLDS
190 200 210 220 230 240
VPIVAITGQV PRRMIGTDAF QETPIVEVTR SITKHNYLVM DVEDIPRVVR EAFFLARSGR
250 260 270 280 290 300
PGPVLIDVPK DIQQQLVIPD WDQPMRLPGY MSRLPKLPNE MLLEQIVRLI SESKKPVLYV
310 320 330 340 350 360
GGGCSQSSEE LRRFVELTGI PVASTLMGLG AFPTGDELSL SMLGMHGTVY ANYAVDSSDL
370 380 390 400 410 420
LLAFGVRFDD RVTGKLEAFA SRAKIVHIDI DSAEIGKNKQ PHVSICADIK LALQGLNSIL
430 440 450 460 470 480
ESKEGKLKLD FSAWRQELTV QKVKYPLNFK TFGDAIPPQY AIQVLDELTN GSAIISTGVG
490 500 510 520 530 540
QHQMWAAQYY KYRKPRQWLT SGGLGAMGFG LPAAIGAAVG RPDEVVVDID GDGSFIMNVQ
550 560 570 580 590 600
ELATIKVENL PVKIMLLNNQ HLGMVVQWED RFYKANRAHT YLGNPSNEAE IFPNMLKFAE
610 620 630 640 650 660
ACGVPAARVT HRDDLRAAIQ KMLDTPGPYL LDVIVPHQEH VLPMIPSGGA FKDVITEGDG
RSSY