P08992

PR
Gene name
HTA3 (HV1, TTHERM_00143660)
Protein name
Histone H2A.Z
Names
hv1
Species
Tetrahymena thermophila (strain SB210)
KEGG Pathway
tet:TTHERM_00143660
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-62 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P08992

Entry ID Method Resolution Chain Position Source
AF-P08992-F1 Predicted AlphaFoldDB

No variants for P08992

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P08992

No associated diseases with P08992

3 regional properties for P08992

Type Name Position InterPro Accession
domain Histone H2A/H2B/H3 21 - 103 IPR007125
domain Histone H2A, C-terminal domain 105 - 136 IPR032454
conserved_site Histone H2A conserved site 34 - 40 IPR032458

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Chromosome
  • Localizes to the large, transcriptionally active, somatic macronucleus (MAC) at all stages of the cell cycle
  • Usually absent from the small, transcriptionally inert, germ line micronucleus (MIC), it is shortly found in the MIC during an early stage of conjugation
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nucleosome A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.
structural constituent of chromatin The action of a molecule that contributes to the structural integrity of chromatin.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGGKGGKGG KGGKGGKVGG AKNKKTPQSR SYKAGLQFPV GRIHRFLKGR VSAKNRVGAT
70 80 90 100 110 120
AAVYAAAILE YLTAEVLELA GNASKDFKVR RITPRHLLLA IRGDEELDIL IKATIAGGGV
130 140
IPHIHKALLG KHSTKNRSSA KTAEPR