P08800

PR
Gene name
uppA (DDB_G0289875)
Protein name
UTP--glucose-1-phosphate uridylyltransferase 1
Names
UDP-glucose pyrophosphorylase 1, UDPGP 1, UGPase 1
Species
Dictyostelium discoideum (Slime mold)
KEGG Pathway
ddi:DDB_G0289875
EC number
2.7.7.9: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-146 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P08800

Entry ID Method Resolution Chain Position Source
AF-P08800-F1 Predicted AlphaFoldDB

No variants for P08800

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P08800

No associated diseases with P08800

2 regional properties for P08800

Type Name Position InterPro Accession
conserved_site Isocitrate lyase/phosphorylmutase, conserved site 211 - 216 IPR018523
domain ICL/PEPM domain 75 - 489 IPR039556

Functions

Description
EC Number 2.7.7.9 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
UTP:glucose-1-phosphate uridylyltransferase activity Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.

4 GO annotations of biological process

Name Definition
culmination involved in sorocarp development The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
galactose metabolic process The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
glycogen metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
UDP-glucose metabolic process The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDTATSKAT VERPKLQSTG SLHSLFKNVD LFSENDEELY PPLQHGARFA APIEDSTLLA
70 80 90 100 110 120
LGMKPDELKA FQKQRHAYIN KDQIYTDEIK IPNKTEMVDY HQLHLVSPID QSNASRLLNK
130 140 150 160 170 180
LVVIKLNGGL GNSMGCKTAK STMEIAPGVT FLDMAVAHIE QINQDYNVDV PLVIMNSYKT
190 200 210 220 230 240
HNETNKVIEK YKTHKVSIKT FQQSMFPKMY KDTLNLVPKP NTPMNPKEWY PPGSGDIFRS
250 260 270 280 290 300
LQRSGLIDEF LAAGKEYIFI SNVENLGSII DLQVLNHIHL QKIEFGLEVT NRINTDSTGG
310 320 330 340 350 360
ILMSYKDKLH LLELSQVKPE KLKIFKDFKL WNTNNIWVNL KSVSNLIKED KLDLDWIVNY
370 380 390 400 410 420
PLENHKAMVQ LETPAGMGIQ NFKNSVAIFV PRDRYRPIKS TSQLLVAQSN IFQFDHGQVK
430 440 450 460 470 480
LNSKREGQDV PLVKLGEEFS TVSDYEKRFK SIPDLLELDH LTVSGDVYFG SRITLKGTVI
490 500 510
IVANHGERVD IPDGVVLENK VLSGTLRILD H