P08196
Gene name |
PSY1 (GTOM5, PTOM5, TOM5) |
Protein name |
Phytoene synthase 1, chloroplastic |
Names |
4F2hc, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2, Fruit-ripening-specific protein pTOM5 |
Species |
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
KEGG Pathway |
sly:543988 |
EC number |
2.5.1.32: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P08196
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P08196-F1 | Predicted | AlphaFoldDB |
17 variants for P08196
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| vcZ154NCN | 29 | R>H | No | Ensembl | |
| vcZ154NCO | 34 | S>P | No | Ensembl | |
| vcZ154NCQ | 48 | G>C | No | Ensembl | |
| vcZ154NCR | 48 | G>V | No | Ensembl | |
| vcZ154NCS | 49 | G>V | No | Ensembl | |
| vcZ154NCT | 56 | G>E | No | Ensembl | |
| vcZ154NCU | 57 | R>Q | No | Ensembl | |
| vcZ154NCV | 62 | R>W | No | Ensembl | |
| vcZ154ND7 | 102 | L>F | No | Ensembl | |
| vcZ154ND6 | 102 | L>I | No | Ensembl | |
| vcZ154NDQ | 144 | P>S | No | Ensembl | |
| vcZ154NGP | 254 | I>V | No | Ensembl | |
| vcZ154NIT | 353 | R>K | No | Ensembl | |
| vcZ154NIU | 354 | F>L | No | Ensembl | |
| vcZ154NLJ | 361 | V>I | No | Ensembl | |
| vcZ154NLN | 408 | A>V | No | Ensembl | |
| vcZ154NLO | 410 | L>P | No | Ensembl |
No associated diseases with P08196
3 regional properties for P08196
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Squalene/phytoene synthase, conserved site | 239 - 254 | IPR019845-1 |
| conserved_site | Squalene/phytoene synthase, conserved site | 275 - 300 | IPR019845-2 |
| domain | Trans-isoprenyl diphosphate synthases, head-to-head | 122 - 389 | IPR033904 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.32 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| farnesyltranstransferase activity | Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate. |
| geranylgeranyl-diphosphate geranylgeranyltransferase activity | Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carotenoid biosynthetic process | The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSVALLWVVS | PCDVSNGTSF | MESVREGNRF | FDSSRHRNLV | SNERINRGGG | KQTNNGRKFS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VRSAILATPS | GERTMTSEQM | VYDVVLRQAA | LVKRQLRSTN | ELEVKPDIPI | PGNLGLLSEA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YDRCGEVCAE | YAKTFNLGTM | LMTPERRRAI | WAIYVWCRRT | DELVDGPNAS | YITPAALDRW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ENRLEDVFNG | RPFDMLDGAL | SDTVSNFPVD | IQPFRDMIEG | MRMDLRKSRY | KNFDELYLYC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YYVAGTVGLM | SVPIMGIAPE | SKATTESVYN | AALALGIANQ | LTNILRDVGE | DARRGRVYLP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QDELAQAGLS | DEDIFAGRVT | DKWRIFMKKQ | IHRARKFFDE | AEKGVTELSS | ASRFPVWASL |
| 370 | 380 | 390 | 400 | 410 | |
| VLYRKILDEI | EANDYNNFTK | RAYVSKSKKL | IALPIAYAKS | LVPPTKTASL | QR |