Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P08196

Entry ID Method Resolution Chain Position Source
AF-P08196-F1 Predicted AlphaFoldDB

17 variants for P08196

Variant ID(s) Position Change Description Diseaes Association Provenance
vcZ154NCN 29 R>H No Ensembl
vcZ154NCO 34 S>P No Ensembl
vcZ154NCQ 48 G>C No Ensembl
vcZ154NCR 48 G>V No Ensembl
vcZ154NCS 49 G>V No Ensembl
vcZ154NCT 56 G>E No Ensembl
vcZ154NCU 57 R>Q No Ensembl
vcZ154NCV 62 R>W No Ensembl
vcZ154ND7 102 L>F No Ensembl
vcZ154ND6 102 L>I No Ensembl
vcZ154NDQ 144 P>S No Ensembl
vcZ154NGP 254 I>V No Ensembl
vcZ154NIT 353 R>K No Ensembl
vcZ154NIU 354 F>L No Ensembl
vcZ154NLJ 361 V>I No Ensembl
vcZ154NLN 408 A>V No Ensembl
vcZ154NLO 410 L>P No Ensembl

No associated diseases with P08196

3 regional properties for P08196

Type Name Position InterPro Accession
conserved_site Squalene/phytoene synthase, conserved site 239 - 254 IPR019845-1
conserved_site Squalene/phytoene synthase, conserved site 275 - 300 IPR019845-2
domain Trans-isoprenyl diphosphate synthases, head-to-head 122 - 389 IPR033904

Functions

Description
EC Number 2.5.1.32 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

2 GO annotations of molecular function

Name Definition
farnesyltranstransferase activity Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
geranylgeranyl-diphosphate geranylgeranyltransferase activity Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.

1 GO annotations of biological process

Name Definition
carotenoid biosynthetic process The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSVALLWVVS PCDVSNGTSF MESVREGNRF FDSSRHRNLV SNERINRGGG KQTNNGRKFS
70 80 90 100 110 120
VRSAILATPS GERTMTSEQM VYDVVLRQAA LVKRQLRSTN ELEVKPDIPI PGNLGLLSEA
130 140 150 160 170 180
YDRCGEVCAE YAKTFNLGTM LMTPERRRAI WAIYVWCRRT DELVDGPNAS YITPAALDRW
190 200 210 220 230 240
ENRLEDVFNG RPFDMLDGAL SDTVSNFPVD IQPFRDMIEG MRMDLRKSRY KNFDELYLYC
250 260 270 280 290 300
YYVAGTVGLM SVPIMGIAPE SKATTESVYN AALALGIANQ LTNILRDVGE DARRGRVYLP
310 320 330 340 350 360
QDELAQAGLS DEDIFAGRVT DKWRIFMKKQ IHRARKFFDE AEKGVTELSS ASRFPVWASL
370 380 390 400 410
VLYRKILDEI EANDYNNFTK RAYVSKSKKL IALPIAYAKS LVPPTKTASL QR