AiPD: Autoinhibited Protein Database

Gene name	cotA
Protein name	Laccase
Names	Bilirubin oxidase, Spore coat protein A
Species	Bacillus subtilis (strain 168)
KEGG Pathway	bsu:BSU06300
EC number	1.3.3.5: With oxygen as acceptor
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-135 (Predicted disordered autoinhibitory region) PR

1-135 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
1GSK	X-ray	170 A	A	1-513	PDB
1OF0	X-ray	245 A	A	1-513	PDB
1W6L	X-ray	200 A	A	1-513	PDB
1W6W	X-ray	220 A	A	1-513	PDB
1W8E	X-ray	220 A	A	1-513	PDB
2BHF	X-ray	250 A	A	1-513	PDB
2WSD	X-ray	160 A	A	1-513	PDB
2X87	X-ray	200 A	A	1-513	PDB
2X88	X-ray	180 A	A	1-513	PDB
3ZDW	X-ray	245 A	A	1-513	PDB
4A66	X-ray	195 A	A	1-513	PDB
4A67	X-ray	210 A	A	1-513	PDB
4A68	X-ray	200 A	A	1-513	PDB
4AKO	X-ray	170 A	A	1-513	PDB
4AKP	X-ray	200 A	A	1-513	PDB
4AKQ	X-ray	210 A	A	1-513	PDB
4Q89	X-ray	231 A	A/B	1-513	PDB
4Q8B	X-ray	191 A	A/B	1-513	PDB
4YVN	X-ray	230 A	A	1-513	PDB
4YVU	X-ray	230 A	A	1-513	PDB
5ZLJ	X-ray	196 A	A	1-513	PDB
5ZLK	X-ray	260 A	A	1-513	PDB
5ZLL	X-ray	260 A	A	1-513	PDB
5ZLM	X-ray	170 A	A	1-513	PDB
7Y8B	X-ray	200 A	A/B	1-513	PDB
7Y8C	X-ray	200 A	A/B	1-513	PDB
AF-P07788-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
No variants for P07788

Type	Name	Position	InterPro Accession
domain	Multicopper oxidase, second cupredoxin domain	240 - 318	IPR001117
domain	Multicopper oxidase, C-terminal	378 - 509	IPR011706
domain	Multicopper oxidase, N-terminal	45 - 81	IPR011707-1
domain	Multicopper oxidase, N-terminal	101 - 178	IPR011707-2

		Description
EC Number	1.3.3.5	With oxygen as acceptor
Subcellular Localization	Spore coat	Localized to the surface layers of the endospore
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
outer membrane-bounded periplasmic space	The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.

Name	Definition
copper ion binding	Binding to a copper (Cu) ion.
oxidoreductase activity	Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

Name	Definition
sporulation resulting in formation of a cellular spore	The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins