P07654

PR
Gene name
pstA (phoT, b3726, JW3704)
Protein name
Phosphate transport system permease protein PstA
Names
Species
Escherichia coli (strain K12)
KEGG Pathway
eco:b3726
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P07654

Entry ID Method Resolution Chain Position Source
AF-P07654-F1 Predicted AlphaFoldDB

No variants for P07654

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P07654

No associated diseases with P07654

1 regional properties for P07654

Type Name Position InterPro Accession
domain ABC transporter type 1, transmembrane domain MetI-like 83 - 289 IPR000515

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

1 GO annotations of molecular function

Name Definition
inorganic phosphate transmembrane transporter activity Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Secondary active transporters include symporters and antiporters.

4 GO annotations of biological process

Name Definition
cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
phosphate ion transmembrane transport The process in which a phosphate is transported across a membrane.
phosphate ion transport The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
regulation of phosphatase activity Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAMVEMQTTA ALAESRRKMQ ARRRLKNRIA LTLSMATMAF GLFWLIWILM STITRGIDGM
70 80 90 100 110 120
SLALFTEMTP PPNTEGGGLA NALAGSGLLI LWATVFGTPL GIMAGIYLAE YGRKSWLAEV
130 140 150 160 170 180
IRFINDILLS APSIVVGLFV YTIVVAQMEH FSGWAGVIAL ALLQVPIVIR TTENMLKLVP
190 200 210 220 230 240
YSLREAAYAL GTPKWKMISA ITLKASVSGI MTGILLAIAR IAGETAPLLF TALSNQFWST
250 260 270 280 290
DMMQPIANLP VTIFKFAMSP FAEWQQLAWA GVLIITLCVL LLNILARVVF AKNKHG