P07284
Gene name |
SES1 (SERS) |
Protein name |
Serine--tRNA ligase, cytoplasmic |
Names |
Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase |
Species |
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
KEGG Pathway |
sce:YDR023W |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P07284
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P07284-F1 | Predicted | AlphaFoldDB |
1 variants for P07284
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| s04-489821 | 106 | F>S | No | SGRP |
No associated diseases with P07284
4 regional properties for P07284
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) | 232 - 419 | IPR002314 |
| domain | Aminoacyl-tRNA synthetase, class II | 197 - 428 | IPR006195 |
| domain | Serine-tRNA synthetase, type1, N-terminal | 1 - 112 | IPR015866 |
| domain | Serine-tRNA ligase catalytic core domain | 124 - 435 | IPR033729 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| cytoplasmic stress granule | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| serine-tRNA ligase activity | Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). |
| tRNA binding | Binding to a transfer RNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| selenocysteinyl-tRNA(Sec) biosynthetic process | The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA |
| seryl-tRNA aminoacylation | The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. The seryl-tRNA synthetase is a class-II synthetase. The activated amino acid is transferred to the 3'-OH group of a serine-accetping tRNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLDINQFIED | KGGNPELIRQ | SQKARNASVE | IVDEIISDYK | DWVKTRFELD | ELNKKFNKLQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KDIGLKFKNK | EDASGLLAEK | EKLTQQKKEL | TEKEQQEDKD | LKKKVFQVGN | IVHPSVVVSN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DEENNELVRT | WKPEDLEAVG | PIASVTGKPA | SLSHHEILLR | LDGYDPDRGV | KICGHRGYFF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RNYGVFLNQA | LINYGLQFLA | AKGYIPLQAP | VMMNKELMSK | TAQLSEFDEE | LYKVIDGEDE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KYLIATSEQP | ISAYHSGEWF | EKPQEQLPIH | YVGYSSCFRR | EAGSHGKDAW | GVFRVHAFEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IEQFVITEPE | KSWEEFEKMI | SYSEEFYKSL | KLPYRIVGIV | SGELNNAAAK | KYDLEAWFPY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QKEYKELVSC | SNCTDYQSRN | LEIRCGIKKM | GDREKKYVHC | LNSTLAATQR | ALCCILENYQ |
| 430 | 440 | 450 | 460 | ||
| TEDGLVVPEV | LRKYIPGEPE | FLPFVNELPK | NSTSSKDKKK | KN |