Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for P07145

Entry ID Method Resolution Chain Position Source
AF-P07145-F1 Predicted AlphaFoldDB

No variants for P07145

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P07145

No associated diseases with P07145

4 regional properties for P07145

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 344 - 352 IPR002226
domain Catalase immune-responsive domain 422 - 486 IPR010582
domain Catalase core domain 18 - 401 IPR011614
active_site Catalase active site 54 - 70 IPR024708

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Cytoplasm, cytosol
  • Peroxisome matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDPSKYRPSS SFNTPFCTTN SGAPVWNNTC ALTVGSRGPI LLEDYHLVEK IQNFTRERIP
70 80 90 100 110 120
ERVVHARGAS AKGFFEVTHD ITHLTCADFL RAPGVQTPLI VRFSTVIHER GSPETIRDPR
130 140 150 160 170 180
GFAVKMYTRG GNWDLVGNNF PVFFIRDGTQ FPDVIHAFKP NPKSHIQENW RILDYLSHLP
190 200 210 220 230 240
ESLNTFAWFY DDVGIPTDYR HMEGFGVHTF TMINKEGKAN YVKFHWKPTC GVKCLLEEEA
250 260 270 280 290 300
IRIGGENHSH ATQDLYESIA AGNYPEWKLY IQVMDPDHED RFDFDPLDTT KIWPEELIPL
310 320 330 340 350 360
QPVGRMVLNK NIDNFFAENE MLAMDPAHIV PGIYFSDDKM LQARVFAYAD THRHRLGPNY
370 380 390 400 410 420
MLLPVNAPKC AHHNNSYDGY MNFVHRDEEV DYFPSKFDNT RNAERFPTPL RIVTGQRDKC
430 440 450 460 470 480
VIEKENNFKQ PGDRYRSWAP DRQDRFINRW VKALSEPRVT HEIRSTWISY LTQADRSLGQ
490
KVASRLNIRP TM