P06857
Gene name |
PNLIPRP1 (PLRP1) |
Protein name |
Inactive pancreatic lipase-related protein 1 |
Names |
PL-RP1 |
Species |
Canis lupus familiaris (Dog) (Canis familiaris) |
KEGG Pathway |
cfa:404010 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for P06857
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1RP1 | X-ray | 210 A | A | 18-467 | PDB |
| AF-P06857-F1 | Predicted | AlphaFoldDB |
1 variants for P06857
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs850657026 | 314 | C>W | No | EVA |
No associated diseases with P06857
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
| carboxylic ester hydrolase activity | Catalysis of the hydrolysis of a carboxylic ester bond. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid catabolic process | The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVSIWTIALF | LLGAAKAKEV | CYEQIGCFSD | AEPWAGTAIR | PLKVLPWSPE | RIGTRFLLYT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NKNPNNFQTL | LPSDPSTIEA | SNFQTDKKTR | FIIHGFIDKG | EENWLLDMCK | NMFKVEEVNC |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ICVDWKKGSQ | TSYTQAANNV | RVVGAQVAQM | LSMLSANYSY | SPSQVQLIGH | SLGAHVAGEA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GSRTPGLGRI | TGLDPVEASF | QGTPEEVRLD | PTDADFVDVI | HTDAAPLIPF | LGFGTSQQMG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HLDFFPNGGE | EMPGCKKNAL | SQIVDLDGIW | EGTRDFVACN | HLRSYKYYSE | SILNPDGFAS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| YPCASYRAFE | SNKCFPCPDQ | GCPQMGHYAD | KFAVKTSDET | QKYFLNTGDS | SNFARWRYGV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SITLSGKRAT | GQAKVALFGS | KGNTHQFNIF | KGILKPGSTH | SNEFDAKLDV | GTIEKVKFLW |
| 430 | 440 | 450 | 460 | ||
| NNNVVNPTFP | KVGAAKITVQ | KGEEKTVHSF | CSESTVREDV | LLTLTPC |