P06222

PR
Gene name
sigE (spoIIGB, BSU15320)
Protein name
RNA polymerase sigma-E factor
Names
P31, Sigma-29, Stage II sporulation protein GB
Species
Bacillus subtilis (strain 168)
KEGG Pathway
bsu:BSU15320
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-76 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P06222

Entry ID Method Resolution Chain Position Source
AF-P06222-F1 Predicted AlphaFoldDB

No variants for P06222

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P06222

No associated diseases with P06222

No regional properties for P06222

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P06222

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
sigma factor activity Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.

2 GO annotations of biological process

Name Definition
DNA-templated transcription initiation The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.
sporulation resulting in formation of a cellular spore The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKLKLRLTH LWYKLLMKLG LKSDEVYYIG GSEALPPPLS KDEEQVLLMK LPNGDQAARA
70 80 90 100 110 120
ILIERNLRLV VYIARKFENT GINIEDLISI GTIGLIKAVN TFNPEKKIKL ATYASRCIEN
130 140 150 160 170 180
EILMYLRRNN KIRSEVSFDE PLNIDWDGNE LLLSDVLGTD DDIITKDIEA NVDKKLLKKA
190 200 210 220 230
LEQLNEREKQ IMELRFGLVG EEEKTQKDVA DMMGISQSYI SRLEKRIIKR LRKEFNKMV