P06187
Gene name |
hsdS |
Protein name |
Type I restriction enzyme StySJI specificity subunit |
Names |
S protein, Type I restriction and modification system SB, Type I specificity subunit S.StySJI, S.StySJI, Type-1 restriction enzyme StySJI specificity subunit |
Species |
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) |
KEGG Pathway |
stm:STM4524 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P06187
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P06187-F1 | Predicted | AlphaFoldDB |
No variants for P06187
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P06187 | |||||
No associated diseases with P06187
2 regional properties for P06187
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Type I restriction modification DNA specificity domain | 7 - 187 | IPR000055-1 |
| domain | Type I restriction modification DNA specificity domain | 225 - 409 | IPR000055-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA restriction-modification system | A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGGKLPEGW | ATSTINEMCN | LNPKLKLDDD | LDVGFMPMAG | VPTTYLGKCN | FETKKWSEVK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KGFTQFQNDD | VIFAKITPCF | ENGKAVVIKE | FPNGYGAGST | EYYVLRSING | LINPHWLFAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VKTKDFLTNG | ALNMSGSVGH | KRVTKEFLEN | YGVPVPPLAE | QKVIAEKLDT | LLAQVDSTKA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RLEQIPQILK | RFRQSVIVAA | VNGQLTKELH | KKNKFKLTEL | NISIPSLWKI | SEIGQFADVK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GGKRLPKGES | LIAENTGFPY | IRAGQLKNGT | VLPEGQLYLE | EYIQKSISRY | TVSSGDLYIT |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IVGACIGDAG | IIPDVYNNAN | LTENAAKICN | LNENIFNRFL | SLWLRSSYLQ | DIINSEIKSG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AQGKLALARI | KSLPLILPPL | QEQHEIVRRV | EQLFAYADTI | EKQVNNALTR | VNSLTQSILA |
| 430 | 440 | 450 | 460 | ||
| KAFRGELTAQ | WRAENPELIS | GENSAAALLE | KIKAERAASG | GKKTSRKKA |