Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for P06165
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for P06165
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P06165 | |||||
No associated diseases with P06165
No regional properties for P06165
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for P06165 | |||
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1). |
| suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2). |
| suppression by virus of host type I interferon-mediated signaling pathway | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLKTIKSWIL | GKRNQEINQL | ISPRPSTSLN | SYSAPTPKKT | YRKTTQSTQE | PSNSAPPSVN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QKSNQQKQVK | KLVDQLTKID | SLGHHTNVQQ | KQKIEILIRK | LYREDLGEEA | AQIVELRLWS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LEESLEASQI | LKMEPKTRRI | LISMKLERWI | RTLLRGKCDN | LQMFQARYQE | VMSYLQQNKV |
| 190 | |||||
| ETVIMEEAWN | LSVHLIQDQ |