Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for P05846
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1T0F | X-ray | 185 A | C/D | 503-555 | PDB |
| 7MCS | EM | 356 A | A/B/C/D/E/F/G | 1-503 | PDB |
| AF-P05846-F1 | Predicted | AlphaFoldDB |
No variants for P05846
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P05846 | |||||
No associated diseases with P05846
1 regional properties for P05846
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | AAA+ ATPase domain | 126 - 292 | IPR003593 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA recombination | Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Interchromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction. |
| transposition | Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSATRIQAVY | RDTGVEAYRD | NPFIEALPPL | QESVNSAASL | KSSLQLTSSD | LQKSRVIRAH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TICRIPDDYF | QPLGTHLLLS | ERISVMIRGG | YVGRNPKTGD | LQKHLQNGYE | RVQTGELETF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RFEEARSTAQ | SLLLIGCSGS | GKTTSLHRIL | ATYPQVIYHR | ELNVEQVVYL | KIDCSHNGSL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KEICLNFFRA | LDRALGSNYE | RRYGLKRHGI | ETMLALMSQI | ANAHALGLLV | IDEIQHLSRS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RSGGSQEMLN | FFVTMVNIIG | VPVMLIGTPK | AREIFEADLR | SARRGAGFGA | IFWDPIQQTQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RGKPNQEWIA | FTDNLWQLQL | LQRKDALLSD | EVRDVWYELS | QGVMDIVVKL | FVLAQLRALA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LGNERITAGL | LRQVYQDELK | PVHPMLEALR | SGIPERIARY | SDLVVPEIDK | RLIQLQLDIA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| AIQEQTPEEK | ALQELDTEDQ | RHLYLMLKED | YDSSLLIPTI | KKAFSQNPTM | TRQKLLPLVL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| QWLMEGETVV | SELEKPSKSK | KVSAIKVVKP | SDWDSLPDTD | LRYIYSQRQP | EKTMHERLKG |
| 550 | |||||
| KGVIVDMASL | FKQAG |