Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P05548
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P05548-F1 | Predicted | AlphaFoldDB |
1 variants for P05548
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| 113 | D>E | No |
No associated diseases with P05548
8 regional properties for P05548
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| binding_site | IQ motif, EF-hand binding site | 35 - 62 | IPR000048 |
| domain | Immunoglobulin subtype 2 | 71 - 139 | IPR003598-1 |
| domain | Immunoglobulin subtype 2 | 165 - 232 | IPR003598-2 |
| domain | Immunoglobulin subtype | 65 - 150 | IPR003599-1 |
| domain | Immunoglobulin subtype | 159 - 243 | IPR003599-2 |
| domain | Immunoglobulin-like domain | 59 - 148 | IPR007110 |
| domain | Immunoglobulin I-set | 59 - 148 | IPR013098-1 |
| domain | Immunoglobulin I-set | 155 - 242 | IPR013098-2 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| PKPPAEAKPA | AKPAAPPAAA | NPFEGVDVKD | PIVISAATRI | QASFRMHKNR | MALKEKSIPK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FSQVLKDMFV | MEGSAVTFFA | RVWGIPDPVI | KWFKDGQEVK | QGPKHEIKFD | DKDGTFLIIR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NADGDDVGTY | TCQATNSFGE | AFDSARLALE | VPAKCTKQPD | NITVKAGGNF | EIKVEIAGEP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EPDVIWTKGK | KEIDEGGRFS | YEDSPDYSIL | RVEKAQAGDA | GKYEIEIVND | LGKARAYCTV |
| KVN |