P05133

PR
Gene name
N
Protein name
Nucleoprotein
Names
Nucleocapsid protein, Protein N
Species
Hantaan virus (strain 76-118) (Korean hemorrhagic fever virus)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-114 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for P05133

Entry ID Method Resolution Chain Position Source
4FI5 X-ray 220 A A 3-93 PDB
5FSG X-ray 321 A A 113-429 PDB
6I2N EM 330 A D 1-429 PDB

No variants for P05133

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P05133

No associated diseases with P05133

No regional properties for P05133

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P05133

Functions

Description
EC Number
Subcellular Localization
  • Virion
  • Host cytoplasm, host perinuclear region
  • Host Golgi apparatus, host cis-Golgi network
  • Internal protein of virus particle
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
helical viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.
host cell Golgi apparatus A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
host cell perinuclear region of cytoplasm The host cell cytoplasm situated near, or occurring around, the host nucleus.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
viral nucleocapsid The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.

2 GO annotations of molecular function

Name Definition
endonuclease activity Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
suppression by virus of host apoptotic process Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATMEELQRE INAHEGQLVI ARQKVRDAEK QYEKDPDELN KRTLTDREGV AVSIQAKIDE
70 80 90 100 110 120
LKRQLADRIA TGKNLGKEQD PTGVEPGDHL KERSMLSYGN VLDLNHLDID EPTGQTADWL
130 140 150 160 170 180
SIIVYLTSFV VPILLKALYM LTTRGRQTTK DNKGTRIRFK DDSSFEDVNG IRKPKHLYVS
190 200 210 220 230 240
LPNAQSSMKA EEITPGRYRT AVCGLYPAQI KARQMISPVM SVIGFLALAK DWSDRIEQWL
250 260 270 280 290 300
IEPCKLLPDT AAVSLLGGPA TNRDYLRQRQ VALGNMETKE SKAIRQHAEA AGCSMIEDIE
310 320 330 340 350 360
SPSSIWVFAG APDRCPPTCL FIAGIAELGA FFSILQDMRN TIMASKTVGT SEEKLRKKSS
370 380 390 400 410 420
FYQSYLRRTQ SMGIQLGQRI IVLFMVAWGK EAVDNFHLGD DMDPELRTLA QSLIDVKVKE
ISNQEPLKL