P04530
Gene name |
41 |
Protein name |
DnaB-like replicative helicase |
Names |
Gene product 41, Gp41 |
Species |
Enterobacteria phage T4 (Bacteriophage T4) |
KEGG Pathway |
vg:1258700 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
8 structures for P04530
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 8DTP | EM | 270 A | A/B/C/D/E/F | 1-475 | PDB |
| 8DUE | EM | 290 A | A/B/C/D/E/F | 1-432 | PDB |
| 8DUO | EM | 570 A | A/B/C/D/E/F | 1-475 | PDB |
| 8DVF | EM | 330 A | A/B/C/D/E/F | 1-432 | PDB |
| 8DVI | EM | 320 A | A/B/C/D/E/F | 1-475 | PDB |
| 8DW6 | EM | 350 A | A/B/C/D/E/F | 1-475 | PDB |
| 8G0Z | EM | 361 A | A/B/C/D/E/F | 1-432 | PDB |
| 8GAO | EM | 410 A | A/B/C/D/E/F | 1-432 | PDB |
No variants for P04530
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P04530 | |||||
No associated diseases with P04530
1 regional properties for P04530
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | DNA helicase, DnaB-like, C-terminal | 165 - 444 | IPR007694 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA helicase activity | Unwinding of a DNA helix, driven by ATP hydrolysis. |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| single-stranded DNA helicase activity | Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| bidirectional double-stranded viral DNA replication | A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions. |
| DNA replication, synthesis of RNA primer | The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVEIILSHLI | FDQAYFSKVW | PYMDSEYFES | GPAKNTFKLI | KSHVNEYHSV | PSINALNVAL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ENSSFTETEY | SGVKTLISKL | ADSPEDHSWL | VKETEKYVQQ | RAMFNATSKI | IEIQTNAELP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEKRNKKMPD | VGAIPDIMRQ | ALSISFDSYV | GHDWMDDYEA | RWLSYMNKAR | KVPFKLRILN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KITKGGAETG | TLNVLMAGVN | VGKSLGLCSL | AADYLQLGHN | VLYISMEMAE | EVCAKRIDAN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MLDVSLDDID | DGHISYAEYK | GKMEKWREKS | TLGRLIVKQY | PTGGADANTF | RSLLNELKLK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KNFVPTIIIV | DYLGICKSCR | IRVYSENSYT | TVKAIAEELR | ALAVETETVL | WTAAQVGKQA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| WDSSDVNMSD | IAESAGLPAT | ADFMLAVIET | EELAAAEQQL | IKQIKSRYGD | KNKWNKFLMG |
| 430 | 440 | 450 | 460 | 470 | |
| VQKGNQKWVE | IEQDSTPTEV | NEVAGSQQIQ | AEQNRYQRNE | STRAQLDALA | NELKF |