P03870

PR
Gene name
FLP1 (R0010W)
Protein name
Site-specific recombinase Flp
Names
FLP, Protein Able
Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

94-168 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

4 structures for P03870

Entry ID Method Resolution Chain Position Source
1FLO X-ray 265 A A/B/C/D 2-423 PDB
1M6X X-ray 280 A A/B/C/D 1-423 PDB
1P4E X-ray 270 A PDB
AF-P03870-F1 Predicted AlphaFoldDB

No variants for P03870

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P03870

No associated diseases with P03870

2 regional properties for P03870

Type Name Position InterPro Accession
domain TRP, C-terminal 166 - 596 IPR010308
domain ML-like domain 24 - 162 IPR032800

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
DNA binding, bending The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
double-stranded DNA binding Binding to double-stranded DNA.
single-stranded DNA binding Binding to single-stranded DNA.
site-specific recombinase activity Catalysis of the formation of new phosphodiester bonds between a pair of short, unique target DNA sequences.

2 GO annotations of biological process

Name Definition
DNA integration The process in which a DNA segment is incorporated into another, usually larger, DNA molecule such as a chromosome.
plasmid recombination A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPQFGILCKT PPKVLVRQFV ERFERPSGEK IALCAAELTY LCWMITHNGT AIKRATFMSY
70 80 90 100 110 120
NTIISNSLSF DIVNKSLQFK YKTQKATILE ASLKKLIPAW EFTIIPYYGQ KHQSDITDIV
130 140 150 160 170 180
SSLQLQFESS EEADKGNSHS KKMLKALLSE GESIWEITEK ILNSFEYTSR FTKTKTLYQF
190 200 210 220 230 240
LFLATFINCG RFSDIKNVDP KSFKLVQNKY LGVIIQCLVT ETKTSVSRHI YFFSARGRID
250 260 270 280 290 300
PLVYLDEFLR NSEPVLKRVN RTGNSSSNKQ EYQLLKDNLV RSYNKALKKN APYSIFAIKN
310 320 330 340 350 360
GPKSHIGRHL MTSFLSMKGL TELTNVVGNW SDKRASAVAR TTYTHQITAI PDHYFALVSR
370 380 390 400 410 420
YYAYDPISKE MIALKDETNP IEEWQHIEQL KGSAEGSIRY PAWNGIISQE VLDYLSSYIN
RRI