P03264

PR
Gene name
DBP
Protein name
DNA-binding protein
Names
DBP, Early 2A protein, Early E2A DNA-binding protein
Species
Human adenovirus C serotype 2 (HAdV-2) (Human adenovirus 2)
KEGG Pathway
vg:5739976
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-211 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for P03264

Entry ID Method Resolution Chain Position Source

No variants for P03264

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P03264

No associated diseases with P03264

3 regional properties for P03264

Type Name Position InterPro Accession
domain Adenovirus DNA-binding, all-alpha domain 184 - 262 IPR003176
domain Adenovirus DNA-binding, zinc-binding domain 282 - 383 IPR005376-1
domain Adenovirus DNA-binding, zinc-binding domain 394 - 490 IPR005376-2

Functions

Description
EC Number
Subcellular Localization
  • Host nucleus
  • Accumulates in infected cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
nuclear viral factory A viral factory located in the nucleus of a host cell.
viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
single-stranded DNA binding Binding to single-stranded DNA.
zinc ion binding Binding to a zinc ion (Zn).

5 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
DNA unwinding involved in DNA replication The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
positive regulation of DNA replication Any process that activates or increases the frequency, rate or extent of DNA replication.
viral DNA strand displacement replication A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASREEEQRE TTPERGRGAA RRPPTMEDVS SPSPSPPPPR APPKKRLRRR LESEDEEDSS
70 80 90 100 110 120
QDALVPRTPS PRPSTSTADL AIASKKKKKR PSPKPERPPS PEVIVDSEEE REDVALQMVG
130 140 150 160 170 180
FSNPPVLIKH GKGGKRTVRR LNEDDPVARG MRTQEEKEES SEAESESTVI NPLSLPIVSA
190 200 210 220 230 240
WEKGMEAARA LMDKYHVDND LKANFKLLPD QVEALAAVCK TWLNEEHRGL QLTFTSNKTF
250 260 270 280 290 300
VTMMGRFLQA YLQSFAEVTY KHHEPTGCAL WLHRCAEIEG ELKCLHGSIM INKEHVIEMD
310 320 330 340 350 360
VTSENGQRAL KEQSSKAKIV KNRWGRNVVQ ISNTDARCCV HDAACPANQF SGKSCGMFFS
370 380 390 400 410 420
EGAKAQVAFK QIKAFMQALY PNAQTGHGHL LMPLRCECNS KPGHAPFLGR QLPKLTPFAL
430 440 450 460 470 480
SNAEDLDADL ISDKSVLASV HHPALIVFQC CNPVYRNSRA QGGGPNCDFK ISAPDLLNAL
490 500 510 520
VMVRSLWSEN FTELPRMVVP EFKWSTKHQY RNVSLPVAHS DARQNPFDF