P03185

PR
Gene name
NEC2
Protein name
Nuclear egress protein 2
Names
Species
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
KEGG Pathway
vg:3783699
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

149-324 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P03185

Entry ID Method Resolution Chain Position Source
7T7I X-ray 397 A A/C/E/G/I 1-195 PDB

No variants for P03185

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P03185

No associated diseases with P03185

No regional properties for P03185

Type Name Position InterPro Accession
No domain, repeats, and functional sites for P03185

Functions

Description
EC Number
Subcellular Localization
  • Host nucleus inner membrane ; Single-pass membrane protein
  • Host cytoplasm, host perinuclear region
  • Localizes also at the transient membrane of perinuclear virions
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell nuclear inner membrane The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
viral budding from nuclear membrane A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASPEERLLD ELNNVIVSFL CDSGSLEVER CSGAHVFSRG SSQPLCTVKL RHGQIYHLEF
70 80 90 100 110 120
VYKFLAFKLK NCNYPSSPVF VISNNGLATT LRCFLHEPSG LRSGQSGPCL GLSTDVDLPK
130 140 150 160 170 180
NSIIMLGQDD FIKFKSPLVF PAELDLLKSM VVCRAYITEH RTTMQFLVFQ AANAQKASRV
190 200 210 220 230 240
MDMISDMSQQ LSRSGQVEDT GARVTGGGGP RPGVTHSGCL GDSHVRGRGG WDLDNFSEAE
250 260 270 280 290 300
TEDEASYAPW RDKDSWSESE AAPWKKELVR HPIRRHRTRE TRRMRGSHSR VEHVPPETRE
310 320 330
TVVGGAWRYS WRATPYLARV LAVTAVALLL MFLRWT