P02982

PR
Gene name
tetA
Protein name
Tetracycline resistance protein, class A
Names
TetA(A)
Species
Escherichia coli
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

294-371 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P02982

Entry ID Method Resolution Chain Position Source
AF-P02982-F1 Predicted AlphaFoldDB

No variants for P02982

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P02982

No associated diseases with P02982

2 regional properties for P02982

Type Name Position InterPro Accession
conserved_site Sugar transporter, conserved site 63 - 79 IPR005829
domain Major facilitator superfamily domain 6 - 386 IPR020846

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
antiporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
xenobiotic transmembrane transporter activity Enables the directed movement of a xenobiotic from one side of a membrane to the other. A xenobiotic is a compound foreign to the organim exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.

2 GO annotations of biological process

Name Definition
proton transmembrane transport The directed movement of a proton across a membrane.
response to antibiotic Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKPNRPLIVI LSTVALDAVG IGLIMPVLPG LLRDLVHSND VTAHYGILLA LYALMQFACA
70 80 90 100 110 120
PVLGALSDRF GRRPVLLVSL AGAAVDYAIM ATAPFLWVLY IGRIVAGITG ATGAVAGAYI
130 140 150 160 170 180
ADITDGDERA RHFGFMSACF GFGMVAGPVL GGLMGGFSPH APFFAAAALN GLNFLTGCFL
190 200 210 220 230 240
LPESHKGERR PLRREALNPL ASFRWARGMT VVAALMAVFF IMQLVGQVPA ALWVIFGEDR
250 260 270 280 290 300
FHWDATTIGI SLAAFGILHS LAQAMITGPV AARLGERRAL MLGMIADGTG YILLAFATRG
310 320 330 340 350 360
WMAFPIMVLL ASGGIGMPAL QAMLSRQVDE ERQGQLQGSL AALTSLTSIV GPLLFTAIYA
370 380 390
ASITTWNGWA WIAGAALYLL CLPALRRGLW SGAGQRADR