P02915

PR
Gene name
hisP (STM2351)
Protein name
Histidine transport ATP-binding protein HisP
Names
Species
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
KEGG Pathway
stm:STM2351
EC number
7.4.2.1: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

207-258 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for P02915

Entry ID Method Resolution Chain Position Source
1B0U X-ray 150 A A 1-258 PDB
AF-P02915-F1 Predicted AlphaFoldDB

No variants for P02915

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P02915

No associated diseases with P02915

3 regional properties for P02915

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 7 - 253 IPR003439
domain AAA+ ATPase domain 31 - 230 IPR003593
conserved_site ABC transporter-like, conserved site 154 - 168 IPR017871

Functions

Description
EC Number 7.4.2.1 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein
  • Binds much more tightly to the membrane in the presence of HisQ and HisM
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ABC-type amino acid transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMSENKLHVI DLHKRYGGHE VLKGVSLQAR AGDVISIIGS SGSGKSTFLR CINFLEKPSE
70 80 90 100 110 120
GAIIVNGQNI NLVRDKDGQL KVADKNQLRL LRTRLTMVFQ HFNLWSHMTV LENVMEAPIQ
130 140 150 160 170 180
VLGLSKHDAR ERALKYLAKV GIDERAQGKY PVHLSGGQQQ RVSIARALAM EPDVLLFDEP
190 200 210 220 230 240
TSALDPELVG EVLRIMQQLA EEGKTMVVVT HEMGFARHVS SHVIFLHQGK IEEEGDPEQV
250
FGNPQSPRLQ QFLKGSLK