Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for P01122
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-P01122-F1 | Predicted | AlphaFoldDB |
No variants for P01122
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for P01122 | |||||
No associated diseases with P01122
1 regional properties for P01122
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Small GTP-binding protein domain | 5 - 159 | IPR005225 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| small GTPase mediated signal transduction | The series of molecular signals in which a small monomeric GTPase relays a signal. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAAIRKKLVI | VGDGACGKTC | LLIVFSKDQF | PEVYVPTVFE | NYVADIEVDG | KQVELALWDT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AGQEDYDRLR | PLSYPDTDVI | LMCFSIDSPD | SLENIPEKWT | PEVRHFCPNV | PIILVGNKKD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRNDESTKRE | LMKMKQEPVR | PEDGRAMAEK | INAYSYLECS | AKTKEGVRDV | FETATRAALQ |
| 190 | |||||
| VKKKKKGGCV | VL |