P00640

PR
Gene name
pstIR
Protein name
Type II restriction enzyme PstI
Names
R.PstI, Endonuclease PstI, Type-2 restriction enzyme PstI
Species
Providencia stuartii
KEGG Pathway
EC number
3.1.21.4: Endodeoxyribonucleases producing 5'-phosphomonoesters
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

52-129 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for P00640

Entry ID Method Resolution Chain Position Source
AF-P00640-F1 Predicted AlphaFoldDB

No variants for P00640

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for P00640

No associated diseases with P00640

2 regional properties for P00640

Type Name Position InterPro Accession
domain BsuBI/PstI restriction endonuclease domain 153 - 313 IPR009528
domain BsuBI/PstI restriction endonuclease, HTH domain 5 - 141 IPR041454

Functions

Description
EC Number 3.1.21.4 Endodeoxyribonucleases producing 5'-phosphomonoesters
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
magnesium ion binding Binding to a magnesium (Mg) ion.
type II site-specific deoxyribonuclease activity Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.

1 GO annotations of biological process

Name Definition
DNA restriction-modification system A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKELKLKEAK EILKALGLPP QQYNDRSGWV LLALANIKPE DSWKEAKAPL LPTVSIMEFI
70 80 90 100 110 120
RTEYGKDYKP NSRETIRRQT LHQFEQARIV DRNRDLPSRA TNSKDNNYSL NQVIIDILHN
130 140 150 160 170 180
YPNGNWKELI QQFLTHVPSL QELYERALAR DRIPIKLLDG TQISLSPGEH NQLHADIVHE
190 200 210 220 230 240
FCPRFVGDMG KILYIGDTAS SRNEGGKLMV LDSEYLKKLG VPPMSHDKLP DVVVYDEKRK
250 260 270 280 290 300
WLFLIEAVTS HGPISPKRWL ELEAALSSCT VGKVYVTAFP TRTEFRKNAA NIAWETEVWI
310 320
ADNPDHMVHF NGDRFLGPHD KKPELS